Evidence map›Paper›PMID 41056385›Full record

ArticleScience signaling2025

Phosphorylation of RYR1 at Ser

Rachel Sue Zhen Yee, Chang Seok Lee, Ting Chang, Sung Yun Jung, Omar Yousif, Courtney Cavazos, John Colyer, Filip Van Petegem, George G Rodney, Susan L Hamilton

Abstract read
In one paragraph

Article in Science signaling, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Rachel Sue Zhen YeeDepartment of Integrative Physiology, Baylor College of Medicine, Houston, TX 77030, USA.ORCID 0000-0001-6737-1947
Chang Seok LeeDepartment of Integrative Physiology, Baylor College of Medicine, Houston, TX 77030, USA.ORCID 0000-0002-7513-7621
Ting ChangDepartment of Integrative Physiology, Baylor College of Medicine, Houston, TX 77030, USA.ORCID 0000-0003-0634-6478
Sung Yun JungDepartment of Biochemistry, Baylor College of Medicine, Houston, TX 77030, USA.ORCID 0000-0003-1521-7977
Omar YousifDepartment of Integrative Physiology, Baylor College of Medicine, Houston, TX 77030, USA.
Courtney CavazosDepartment of Integrative Physiology, Baylor College of Medicine, Houston, TX 77030, USA.
John ColyerBadrilla Ltd., Leeds LS1 3HB, UK.
Filip Van PetegemDepartment of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC V6T1Z3, Canada.ORCID 0000-0003-2728-8537
George G RodneyDepartment of Integrative Physiology, Baylor College of Medicine, Houston, TX 77030, USA.ORCID 0000-0002-6968-1516
Susan L HamiltonDepartment of Integrative Physiology, Baylor College of Medicine, Houston, TX 77030, USA.ORCID 0000-0003-0241-9369

Funding

Tumor BiologyP30CA125123 · NCI · BAYLOR COLLEGE OF MEDICINE · PI DAVID R ROWLEY · 2007 to 2026
$73.9M
UM1HG006348: Cas9 Genome Integrity Supplemental ProposalUM1HG006348 · NHGRI · BAYLOR COLLEGE OF MEDICINE · PI Jason D. Heaney, Chih-Wei Logan Hsu · 2016 to 2026
$47.5M
METABOLIC IMPACTS OF TYPE II INTERFERON SIGNALS IN OBESITYR01DK114356 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI HARTIG, SEAN · 2017 to 2025
$4.6M
Nox2-Calcium Signaling in Skeletal MuscleR01AR061370 · NIAMS · BAYLOR COLLEGE OF MEDICINE · PI RODNEY, GEORGE G · 2012 to 2021
$4.1M
Environmental and Epigenetic Modifiers of Susceptibility to Malignant Hyperthermia and Environmental Heat StrokeR01AR082209 · NIAMS · BAYLOR COLLEGE OF MEDICINE · PI JAMES J DOWLING, Robert T Dirksen · 2023 to 2026
$2.9M
Identification of Speg Binding Proteins and Phosphorylation Targets in Skeletal and Cardiac MuscleR21AR082613 · NIAMS · BAYLOR COLLEGE OF MEDICINE · PI JUNG, SUNG YUN, LEE, CHANG SEOK · 2023 to 2023
$387k
Vevo 3100 Ultrasound SystemS10OD032380 · OD · BAYLOR COLLEGE OF MEDICINE · PI WARD, CHRISTOPHER S · 2022 to 2022
$312k
NCI NIH HHS P30 CA125123NHGRI NIH HHS UM1 HG006348NIAMS NIH HHS R01 AR061370NIAMS NIH HHS R01 AR082209NIAMS NIH HHS R21 AR082613NIDDK NIH HHS R01 DK114356NIH HHS S10 OD032380
6 · The paper itself

Abstract

Ryanodine receptor 1 (RYR1) is the sarcoplasmic reticulum (SR) Ca

Indexed as

CalciumHeat StrokeMalignant HyperthermiaMuscle, SkeletalRyanodine Receptor Calcium Release ChannelAnimalsCalcium SignalingMicePhosphorylationPoint MutationSarcoplasmic ReticulumSerineCalciumryanodine receptor 1, mouseRyanodine Receptor Calcium Release ChannelSerine

Identifiers

PMID41056385
PMCPMC12614350

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.