Evidence map›Paper›PMID 41056368›Full record

ArticleJournal of veterinary emergency and critical care (San Antonio, Tex. : 2001)

Retrospective Evaluation of Cryoprecipitate Transfusion in Dogs to Prevent or Treat Hemorrhage: 21 Cases (2009-2023).

W Y Eunice Lam, Linda G Martin, K Jane Wardrop, Jillian M Haines

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Article in Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

W Y Eunice LamDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman, Washington, USA.ORCID https://orcid.org/0000-0003-2005-9125
Linda G MartinDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman, Washington, USA.
K Jane WardropDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman, Washington, USA.
Jillian M HainesDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman, Washington, USA.ORCID https://orcid.org/0000-0002-8066-838X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo report homologous cryoprecipitate transfusions in dogs with hemostatic disorders, hemorrhage, or risk of hemorrhage, and to report adverse reactions associated with these cryoprecipitate transfusions.

designRetrospective case series (July 2009 to July 2023).

settingUniversity teaching hospital. ANIMALS: Twenty-one client-owned dogs with hemostatic disorders, hemorrhage, or risk of procedure-related hemorrhage.

interventionsNone. MEASUREMENTS AND MAIN

resultsAll dogs received homologous cryoprecipitate transfusion. Sixteen dogs had von Willebrand disease (one also had factor XI deficiency); three dogs had hemophilia A; and two dogs had normal concentration of von Willebrand factor and were not diagnosed with any hemostatic disorder. Sixteen dogs also received other blood products and/or hemostatic medications. Twenty-two cryoprecipitate transfusions were administered to 16 dogs before, during, or after surgery; 16 of those 22 transfusions were given to 14 dogs without evidence of hemorrhage but with history of bleeding disorder and/or previous hemorrhage with the aim of preventing hemorrhage. Eight transfusions were given to six dogs to control hemorrhage not associated with surgery. Sixteen dogs (18 transfusions) received cryoprecipitate prepared in-house. Five dogs (12 transfusions) received a commercial lyophilized cryoprecipitate. No dog developed any serious adverse reactions to cryoprecipitate transfusion. All dogs were discharged from the hospital (median, 2 days after cryoprecipitate transfusion [range, 1-25 days]). The benefits of cryoprecipitate transfusion could not be well documented because of the retrospective nature of this study and the concurrent administration of other blood products and/or hemostatic medications to 16 dogs.

conclusionsHomologous cryoprecipitate transfusion appeared to be safe when administered for prevention or treatment of hemorrhage in dogs, but additional studies to assess safety and efficacy are warranted.

Indexed as

Blood TransfusionDog DiseasesFactor VIIIFibrinogenHemorrhageAnimalsDogsFemaleMaleRetrospective Studiescryoprecipitate coagulumFactor VIIIFibrinogencryoprecipitatevon Willebrand diseasevon Willebrand factor

Identifiers

PMID41056368
PMCPMC12614411

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