Evidence map›Paper›PMID 41056249›Full record

ArticlePloS one2025

Diabetes mellitus and associated factors among psychiatric patients receiving antipsychotic treatment at Wachemo University Nigist Elleni Hospital, South Ethiopia.

Amanuel Melaku Laemango, Misgana Bekele Begna, Dembelo Tirago Masebo, Dilebo Lefebo Anshebo, Shifarew Bekele Woyesa, Mengistu Lodebo Funga

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Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Amanuel Melaku LaemangoHosanna College of Health Sciences, Medical Laboratory department.ORCID https://orcid.org/0009-0002-3030-9343
Misgana Bekele BegnaJimma University school of medical laboratory.
Dembelo Tirago MaseboHosanna College of Health Sciences, Medical Laboratory department.
Dilebo Lefebo AnsheboHosanna College of Health Sciences, Medical Laboratory department.
Shifarew Bekele WoyesaJimma University school of medical laboratory.
Mengistu Lodebo FungaHosanna College of Health Sciences, Midwifery Department.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiabetes mellitus is one of the most common non-communicable diseases, and its epidemic proportion has placed it at the forefront of public health challenges currently facing the world. Patients with severe mental illnesses who receive antipsychotic treatment have a high risk of developing metabolic disturbances. METHOD AND MATERIAL: A hospital-based cross-sectional study was conducted. A total of 216 psychiatric patients on treatment were included and selected by consecutive convenient sampling techniques. An interviewer-administered questionnaire was used to collect socio-demographic, clinical, and behavioral characteristics. The levels of fasting blood glucose were measured by Cobas 4000 series Cobas c311Basel, Switzerland. The data were entered into Epi data version 4.6 and analyzed by SPSS version 25. Data were summarized by tables, graphs, and descriptive statistics. Bivariate and multivariate logistic regressions were used. P-value <0.05 was considered statistically significant.

resultA total of 216 psychiatric patients were enrolled in this study. The overall prevalence of diabetes mellitus was 25(11.6%). Among participants with diabetes mellitus, the prevalence of diabetes mellitus was higher in females than males (17(68.0%) vs 8(32.0%). Female (AOR:6.483, 95% CI (1.647, 25.516), P- value = 0.007), longer duration of antipsychotic use (AOR: 7.876 (1.587-39.090), moderate physical activity (AOR: 0.220, 95% CI (.057-.85), P- value = 0.028), higher body mass index (11.869, 95% CI (2.188-64.374), P- value = .004), and high cholesterol(AOR:13.742. 95% CI (3.153-59.887), P- value = .000) were significantly associated to diabetes mellitus.

conclusionThe finding of this study revealed that the prevalence of diabetes mellitus was 11.6%. Female sex, longer duration of antipsychotic use, moderate physical activity, overweight BMI, and high total cholesterol were significantly associated. Therefore, Health providers should regularly weigh patients and monitor long-term side effects of medication.

Indexed as

Antipsychotic AgentsDiabetes MellitusMental DisordersAdolescentAdultBlood GlucoseCross-Sectional StudiesEthiopiaFemaleHumansMaleMiddle AgedPrevalenceRisk FactorsYoung AdultAntipsychotic AgentsBlood Glucose

Identifiers

PMID41056249
PMCPMC12503289

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.