ArticleProceedings of the National Academy of Sciences of the United States of America2025
The intestinal environment potentiates bacteriophage adaptation in response to phenotypic resistance in
Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Detectable effects of bacterial phylogeny on virulence but not phage efficacy in anISME communications · 2026Article
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Authors and funding
11 authors.
Funding
Abstract
Heterogeneous gene expression enables the coexistence of virulent phages with populations of isogenic bacteria comprising both phenotypically phage-resistant and susceptible cells. However, the evolvability of phages and the fitness cost they impose on susceptible bacteria challenge the evolutionary stability of the coexistence. Understanding this dynamic is critical for predicting phage-bacteria coevolution with implications for phage therapy, where resistance hinders treatment success. To address this point, we built on the discovery that heterogeneously expressed alterations of the O-antigen (phase variation) enable phenotypic resistance in
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Registered trials
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