Evidence map›Paper›PMID 41055897›Full record

Trial reportJournal of Parkinson's disease2025

Relating movement behaviours and non-motor characteristics in people with Parkinson's disease: A compositional data analysis approach.

Kristina Larsson, Hanna Johansson, Daniel Peterson, Jenny Sedhed, Breiffni Leavy

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of Parkinson's disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kristina LarssonDepartment of Neurobiology, Care Sciences and Society, Division of Physiotherapy, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0003-4361-6502
Hanna JohanssonDepartment of Neurobiology, Care Sciences and Society, Division of Physiotherapy, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0003-3360-5447
Daniel PetersonCollege of Health Solutions, Arizona State University, Phoenix, Arizona, USA.ORCID 0000-0002-4639-6544
Jenny SedhedDepartment of Neurobiology, Care Sciences and Society, Division of Physiotherapy, Karolinska Institutet, Stockholm, Sweden.ORCID 0009-0008-6630-461X
Breiffni LeavyDepartment of Neurobiology, Care Sciences and Society, Division of Physiotherapy, Karolinska Institutet, Stockholm, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundPeople with Parkinson's disease (PwPD) have unhealthier movement behaviours (less moderate-to-vigorous physical activity (MVPA) and more sedentary behaviour (SB)), than healthy older adults. Associations across movement patterns and non-motor characteristics are poorly understood.ObjectivesTo investigate associations between relative time spent in MVPA, light-intensity physical activities (LIPA) and SB, and non-motor characteristics among PwPD, and to investigate theoretical changes in non-motor characteristics when time in different movement behaviours is reallocated.MethodsBaseline data from 119 participants in the STEPS randomised controlled trial was used. Movement behaviours were measured by ActiGraph GT3X accelerometers. Compositional data analysis assessed relative time in MVPA, LIPA and SB. Linear regression assessed associations between MVPA, LIPA and SB and self-reported anxiety and depression (HADS), executive function (TMT IV), self-efficacy for exercise (S-ESES) and activities-specific balance confidence (ABC). Isotemporal substitution modelling investigated theoretical changes in outcomes when time in MVPA, LIPA and SB were reallocated.ResultsBetter executive function was associated with more relative time in MVPA and less in LIPA. Higher exercise-self-efficacy was associated with more relative time in MVPA and less in SB. Better balance confidence related to more relative time in MVPA. Reallocating time showed that losing 20 min MVPA had a worse theoretical impact for these outcomes than the benefit of gaining 20 min.ConclusionsThe observed relationships between MVPA and executive function, balance confidence, and exercise-self-efficacy suggests particular importance of maintaining MVPA in PwPD. These findings can be utilized clinically by communicating the importance of maintaining time in MVPA among PwPD.

Indexed as

Executive FunctionExerciseParkinson DiseaseSedentary BehaviorSelf EfficacyAccelerometryAgedAnxietyData AnalysisDepressionFemaleHumansMaleMiddle AgedPostural Balancecompositional data analysisnon-motor characteristicsParkinson's diseasephysical activity

Identifiers

PMID41055897
PMCPMC13347681

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.