ArticleJournal of racial and ethnic health disparities2025
Disparities in Stage at Diagnosis and Cancer Progression by Race and Socioeconomic Deprivation: A Pan-Tumor Analysis in the US Community Oncology Setting.
Article in Journal of racial and ethnic health disparities, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeUnderstanding the impact of social determinants of health (SDOH) is essential for addressing cancer disparities. This study evaluated race and area deprivation index (ADI) as proxies for social determinants of early-stage diagnosis and time to metastasis or death (TTMd) among patients with non-metastatic cancers at presenting diagnosis in US community oncology settings.
methodsThis was a retrospective observational cohort study of patients with non-metastatic head and neck squamous cell carcinoma (HNSCC); non-small cell lung cancer (NSCLC); triple-negative (TNBC) or hormone receptor-positive (HR +) breast cancer (BC); gastric, bladder or kidney cancer; or melanoma. Patients were indexed at earliest available cancer diagnosis between 1/1/17-6/30/22 and followed through 6/30/23. Stage within 90 days of the presenting diagnosis and TTMd were assessed by tumor type, race and ADI quintiles. Cox proportional hazards modeling with adjusted hazard ratios (aHR) was used to evaluate associations between race and ADI and TTMd across tumors.
resultsOverall, 109,935 patients were included (54% breast, 20% NSCLC, 26% other). Across several tumor types, a higher proportion of Stage III cancer was observed at presenting diagnosis among Black vs. White patients and with increasing ADI quintiles. Shorter TTMd was associated with higher ADI (Q5, most deprived vs. Q1, least deprived: aHR 1.20, 95% CI 1.15-1.26, P < 0.01; Q4 vs. Q1: aHR 1.18, 95% CI 1.11-1.22, P < 0.01) and Black race (vs. White: aHR 1.07, 95% CI 1.03-1.12, P < 0.01), and these associations varied by tumor type.
conclusionBlack race and socioeconomic deprivation (as measured by the ADI) were associated with more advanced disease at presenting diagnosis and shorter TTMd across multiple tumors. The magnitude of disparities varied across tumor types.
Indexed as
Identifiers
41055876What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.