ArticleAging clinical and experimental research2025
Clinical estimates of three physiologic capacities explain a majority of unipedal stance time.
Article in Aging clinical and experimental research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundRecent prospective research indicates that unipedal stance time (UST) of < 15 s in middle/older adults increases their risk of repetitive falls within 5 to 10 years.
aimTo determine the extent that clinical measures of three physiologic capacities, peripheral afferent acuity, processing speed, and proximal frontal plane strength, are responsible for UST.
methodsUST, distal lower limb clinical vibratory sense, short latency go/no-go accuracy using ReacStick, and lateral plank time, were evaluated in a cohort (n = 172, 51% female, age 64.8 +/- 9.6 years) with diabetic neuropathy (n = 31), cirrhosis (n = 94), and no known neurologic disease (n = 47) using age, body mass index (BMI), sex, and medication number as covariates.
resultsMultivariate analyses demonstrated that the three variables separately, and as a composite variable (vibration time + reaction accuracy/2 + lateral plank time), were associated with UST (adjusted R DISCUSSION: These findings allow clinicians to identify specific physiologic deficits and develop targeted intervention strategies to improve UST.
conclusionClinical estimates of three physiologic capacities predict almost 2/3 of UST variability in middle/older people, rendering age, BMI, sex, and medication number less relevant.
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