Evidence map›Paper›PMID 41055718›Full record

ArticleWiener klinische Wochenschrift2026

Register and biobank on influence of assisted reproduction on pregnancy, maternal and neonatal outcome : A prospective multicenter medical data register and biobank.

Harald Zeisler, Florian Heinzl

Abstract readMulticenter Study
In one paragraph

Article in Wiener klinische Wochenschrift, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Harald ZeislerDepartment of Obstetrics and Gynecology, Medical University Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria. Harald.Zeisler@meduniwien.ac.at.ORCID http://orcid.org/0000-0003-4995-4561
Florian HeinzlDepartment of Obstetrics and Gynecology, Medical University Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInfertility affects 10-15% of couples worldwide. In Austria, the In Vitro Fertilization Fund supports assisted reproductive technology under specific conditions. While assisted reproductive technology is generally effective, its impact on pregnancy and neonatal outcomes remains under discussion.

methodsThe Register and Biobank on the Influence of Assisted Reproduction on Pregnancy, Maternal and Neonatal Outcomes is a prospective multicenter register and biobank. It includes five in vitro fertilization centers and two obstetric departments in Vienna and Lower Austria. Standardized clinical and laboratory data are collected via electronic case report forms and pseudonymized using a unique code linking fertility and obstetric data. Recruitment started in 2022, and biobanking (blood, urine, placenta, and umbilical cord samples) was added in 2025.

resultsBy early 2025, complete data were available for 366 patients. Male infertility was the most frequent indication (231 cases), followed by tubal factor infertility, polycystic ovary syndrome, and endometriosis. The register enables linking of assisted reproductive technology procedures with detailed pregnancy and neonatal outcomes such as Apgar scores, delivery mode, and Neonatal Intensive Care Unit transfers.

conclusionThis register offers a unique real-world dataset connecting assisted reproductive technology treatment with maternal and neonatal outcomes. Continued recruitment will support hypothesis-driven research and improve assisted reproductive technology practices. It underlines the importance of high-quality, longitudinal data to understand potential assisted reproductive technology-related risks and guide future care.

Indexed as

Biological Specimen BanksInfertilityPregnancy ComplicationsPregnancy OutcomeRegistriesReproductive Techniques, AssistedAdultAustriaFemaleHumansInfant, NewbornMalePregnancyProspective StudiesAssisted reproduction technologyFemale factorMale factorObstetrical und neonatal adverse outcomeRegister

Identifiers

PMID41055718
PMCPMC13167881

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.