ReviewMicrobial genomics2025
Lung microbiome dynamics in health and lung cancer.
Review in Microbial genomics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Comment on "Intratumorally specific microbial-derived lipopolysaccharide contributes to non-small cell lung cancer progression".Virulence · 2026Article
- MARM: a framework for malignancy risk prediction from host-derived CNV in bronchoalveolar lavage fluid mNGS data with microbial admixture.Frontiers in microbiology · 2026Article
- [Research Progress on the Regulatory Mechanism of Respiratory Microbiota in the Comorbidity of Chronic Obstructive Pulmonary Disease and Lung Cancer].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Application of culture-independent sequencing technologies has revealed the presence of a low-biomass, high-diversity microbiome within healthy human lungs. This community is highly dynamic, with microbes constantly being introduced into and cleared from healthy airways, and its multifaceted roles in lung physiology and disease are currently a matter of intensive investigation. In view of the rising lung cancer incidence and mortality rates, a large amount of research has already been conducted in the context of lung cancer, suggesting an association between lung cancer and local dysbiosis. In light of these developments, this review summarizes and discusses existing knowledge on lung microbiome dynamics and composition in health and how these differ in lung cancer patients, focusing on the latest research. Throughout this effort, frequently reported alterations and associated microbe-host interactions in lung cancer development and progression are highlighted, along with some critical methodological considerations, outstanding questions and suggestions for the future.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.