Trial reportClinical transplantation2025
Associated Factors to Nonadherence to Routine Appointments after Kidney Transplantation: The ADHERE Brazil Study.
Trial report in Clinical transplantation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02066935 (Non-adherence to Immunosuppressives in Kidney Transplantation in Brazil), which is not on this map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Non-adherence to Immunosuppressives in Kidney Transplantation in Brazil: Diagnosis and Associations - ADHERE BRAZIL Multicenter Study
Who cites it
1 citing paper in PubMed.
- Associated Factors to Nonadherence to Routine Appointments after Kidney Transplantation: The ADHERE Brazil Study.Clinical transplantation · 2025Trial
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
rationaleNonadherence to routine outpatient appointments (NApp) post kidney transplantation (KT) is a poorly studied health behavior associated with unfavorable outcomes. In the ADHERE BRAZIL Study, we previously reported a high prevalence of this behavior (12.7%). AIMS AND
objectiveThis study aimed to identify the multilevel factors associated with NApp after KT.
methodA cross-sectional study, subproject of the ADHERE BRAZIL Study, was performed. We studied a randomized and multi-stage sample of 1105 patients from 20 transplant centers. Patients who missed one or more of the last five scheduled appointments were considered nonadherent. Multivariate analysis was performed using sequential logistic regression, evaluating 49 multilevel variables, according to the Ecological Model (patient, micro, meso, and macro levels).
resultsMost patients were male (58.5%), with a mean age of 47.6 ± 12.6 years. The independent factors associated with NApp were, at the patient level: age (OR 0.97; 95% CI 0.96-0.99; p = 0.001), more than 5 years after KT (OR 2.03; 95% CI 1.38-3.00; p < 0.001), and nonadherence to immunosuppressives (OR 2.41; 95% CI 1.66-3.50; p < 0.001); at the micro level (health professionals): higher scores on the team trust scale (0-100) (OR 0.98; 95% CI 0.95-1.00; p < 0.079), and at the meso level (KT center): frequent (monthly) consultations (OR 1.75; 95% CI 1.10-2.77; p < 0.018) and scheduling difficulties (OR 1.91; 95% CI 1.16-3.17; p < 0.011).
conclusionThis study is the first to examine the association of health system factors with missed appointments after KT. The identified patient factors allow us to recognize patients at risk for NApp. Modifiable variables at the health professional and KT center levels suggest targets for effective interventions aiming to reduce this behavior and improve outcomes.
trial registrationClinicalTrials.gov on 10/10/2013, NCT02066935.
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