Evidence map›Paper›PMID 41055584›Full record

ArticleThe ISME journal2025

Half of microbial eukaryote literature focuses on only 12 human parasites.

Joanna A Lepper, H Beryl Rappaport, Angela M Oliverio

Abstract read
In one paragraph

Article in The ISME journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Joanna A LepperDepartment of Biology, Syracuse University, Syracuse, NY 13210, United States.
H Beryl RappaportDepartment of Biology, Syracuse University, Syracuse, NY 13210, United States.
Angela M OliverioDepartment of Biology, Syracuse University, Syracuse, NY 13210, United States.ORCID 0000-0002-0261-0393

Funding

American Philosophical Society Lewis and Clark Fund for Exploration and Field Research in AstrobiologyNASA #80NSSC25K7916NSF Graduate Research FellowshipSyracuse University Office of Undergraduate Research & Creative EngagementU.S. National Science Foundation #2439029
6 · The paper itself

Abstract

Although microbial eukaryotes comprise the majority of eukaryotic phylogenetic diversity and inhabit nearly all ecosystems globally, most research focuses on only a few species of human parasites. Here, we quantify the extent of research on known microbial eukaryotic species. Nearly half of the mentions of protist species on publications in PubMed referenced only 10 species included in the Protist Ribosomal Reference (PR2) Database. Likewise, although most samples in the PR2 database are free-living protists from aquatic environments, 12 species of human parasites comprise 47% of the literature. Research efforts that focus on only a handful of eukaryotic lineages severely limit our understanding of the fundamental biology of eukaryotic cells. We highlight recent efforts to characterize novel eukaryotic lineages that have resulted in a new understanding of the rules of life and identify key lineages that are notably absent or limited in the literature, despite their abundance and significance across global ecosystems.

Indexed as

BibliometricsEukaryotaParasitesHumansPhylogenybiodiversityeukaryotic tree of lifemicrobial eukaryotesprotists

Identifiers

PMID41055584
PMCPMC12560768

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.