Evidence map›Paper›PMID 41055506›Full record

Trial reportClinical and experimental dental research2025

Polycaprolactone Impregnated 3D Printed Nanohydroxyapatite for Sinus Augmentation: A Randomized Controlled Trial.

Poommarin Thammanoonkul, Suwit Limpattamapanee, Faungchat Thammarakcharoen, Jintamai Suwanprateeb, Hyun-Chang Lim, Borvornwut Buranawat

Abstract readRandomized Controlled TrialMulticenter StudyComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Clinical and experimental dental research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Poommarin ThammanoonkulCenter for Implant Dentistry and Periodontics, Faculty of Dentistry and Research Unit in Innovations in Periodontics, Oral Surgery and Advanced Technology in Implant Dentistry, Thammasat University, Bangkok, Thailand.
Suwit LimpattamapaneeNakhon Ratchasima Provincial Public Health Office, Nakhon Ratchasima, Thailand.
Faungchat ThammarakcharoenBiofunctional Materials and Devices Research Group, National Metal and Materials Technology Center, National Science and Technology Development, Thammasat University, Bangkok, Thailand.
Jintamai SuwanprateebBiofunctional Materials and Devices Research Group, National Metal and Materials Technology Center, National Science and Technology Development, Thammasat University, Bangkok, Thailand.
Hyun-Chang LimCenter for Implant Dentistry and Periodontics, Faculty of Dentistry and Research Unit in Innovations in Periodontics, Oral Surgery and Advanced Technology in Implant Dentistry, Thammasat University, Bangkok, Thailand.ORCID 0000-0001-7695-1708
Borvornwut BuranawatCenter for Implant Dentistry and Periodontics, Faculty of Dentistry and Research Unit in Innovations in Periodontics, Oral Surgery and Advanced Technology in Implant Dentistry, Thammasat University, Bangkok, Thailand.ORCID 0000-0002-5074-584X

Funding

This study was supported by the Thammasat University research fund, Contract No. TUFT 93/64 and Thammasat University-National Science and Technology Development Agency Excellent Research Graduate Scholarship (T2.2-63-01).
6 · The paper itself

Abstract

objectiveTo compare the effect of polycaprolactone impregnated 3D printed nano-hydroxyapatite (3DPHA-PCL) with bovine bone substitute material (BB) in lateral maxillary sinus floor elevation (MSFE). MATERIALS AND

methodsLateral MSFE with two bone substitute materials was randomly performed in two centers: group BB (n = 11 sinuses) or group 3DPHA-PCL (n = 11 sinuses). Lateral MSFE with two bone substitute materials was performed on 21 participants across two centers, resulting in a total of 22 sinuses analyzed. The sinuses were randomly allocated into two groups: group BB (11 sinuses) and group 3DPHA-PCL (11 sinuses). Cone beam computed tomography (CBCT) was taken before (T0) and immediately after MSFE (T1), at 6 months (implant placement; T2), and 1 year (T3). Dimensional stability of the augmentation was analyzed using serial CBCT scans. At the time of implant placement, bone core biopsy was performed, followed by microcomputed tomographic (micro-CT) and histomorphometric analyses.

resultsBased on the superimposed CBCT images between T1 and T2, the augmented height and volume decreased in both groups without a statistically significant difference between the groups (-0.48 ± 1.01 mm, -53.9 ± 117.8 mm

conclusionsDimensional stability of the augmented bone was comparable between the groups. However, group 3DPHA-PCL demonstrated inferior new bone formation and implant survival compared to group BB. Long-term follow-up is warranted to monitor the behavior of 3DPHA-PCL.

Indexed as

Bone SubstitutesDurapatiteMaxillary SinusPolyestersPrinting, Three-DimensionalSinus Floor AugmentationAdultAnimalsCattleCone-Beam Computed TomographyFemaleHumansMaleMiddle AgedX-Ray MicrotomographyBone SubstitutesDurapatitepolycaprolactonePolyestersbone regenerationmaxillary sinus floor elevationpolycaprolactone impregnated 3D printed nano‐hydroxyapatiterandomized clinical trial

Identifiers

PMID41055506
PMCPMC12502625

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.