Evidence map›Paper›PMID 41055359›Full record

ArticlemBio2025

Coordinated regulation of Mdr1- and Cdr1-mediated protection from antifungals by the Mrr1 transcription factor in emerging

Dhanabala-Subhiksha Rajesh-Khanna, Carolina G Piña Páez, Susu He, Elora G Dolan, Kiran S Mirpuri, Jason E Stajich, Deborah A Hogan

Abstract read
In one paragraph

Article in mBio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Comprehensive Insights into Sugar Transporters ofJournal of fungi (Basel, Switzerland) · 2026
    Article
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Dhanabala-Subhiksha Rajesh-KhannaDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.ORCID 0000-0002-0941-8994
Carolina G Piña PáezDepartment of Microbiology & Plant Pathology and Institute for Integrative Genome Biology, University of California-Riverside, Riverside, California, USA.
Susu HeDepartment of Biochemistry and Cell Biology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.
Elora G DolanDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.
Kiran S MirpuriDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.
Jason E StajichDepartment of Microbiology & Plant Pathology and Institute for Integrative Genome Biology, University of California-Riverside, Riverside, California, USA.ORCID 0000-0002-7591-0020
Deborah A HoganDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.ORCID 0000-0002-6366-2971

Funding

Translational Engineering in Cancer (TEC)P30CA023108 · NCI · DARTMOUTH COLLEGE · PI Steven D Leach · 1985 to 2026
$91.3M
Zhao - Proj 2P20GM130454 · NIGMS · DARTMOUTH COLLEGE · PI Chengxiang Qiu · 2019 to 2026
$27.2M
Understanding the role of RNA-binding protein mutations in cancerP20GM113132 · NIGMS · DARTMOUTH COLLEGE · PI MADDEN, DEAN R · 2016 to 2025
$25.9M
Evolution of Aspergillus fumigatus virulenceR01AI130128 · NIAID · DARTMOUTH COLLEGE · PI Robert Andrew Cramer · 2017 to 2026
$4.5M
Evolved Heterogeneity Contributes to Chronic Fungal Lung InfectionsR01AI127548 · NIAID · DARTMOUTH COLLEGE · PI HOGAN, DEBORAH A · 2017 to 2025
$3.9M
Acquisition of a Scalable Storage Cluster for Data Intensive NIH ResearchS10OD016290 · OD · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI GIRKE, THOMAS · 2014 to 2014
$593k
Acquisition of the NextSeq2000 Sequencing platform to Increase Next Generation Sequencing Throughput While Reducing Costs at DartmouthS10OD030242 · OD · DARTMOUTH COLLEGE · PI KOLLING IV, FRED W · 2021 to 2021
$321k
National Science Foundation MRI-1429826National Science Foundation MRI-2215705NCI NIH HHS P30 CA023108NIAID NIH HHS R01 AI127548NIAID NIH HHS R01 AI130128NIGMS NIH HHS P20 GM113132NIGMS NIH HHS P20 GM130454NIH HHS AI127548NIH HHS CA023108NIH HHS GM113132NIH HHS GM130454NIH HHS S10 OD016290NIH HHS S10 OD030242NIH HHS S10OD030242
6 · The paper itself

Abstract

Infections caused by the emerging pathogenic yeast IMPORTANCE: Understanding antifungal resistance in emerging

Indexed as

Antifungal AgentsCandidaFungal ProteinsGene Expression Regulation, FungalMembrane Transport ProteinsTranscription FactorsDrug Resistance, FungalFluconazoleAntifungal AgentsCDR1 protein, Candida albicansFluconazoleFungal ProteinsMembrane Transport ProteinsTranscription FactorsCandida lusitaniaeCUT&RUNMrr1multi-drug transportersresistance

Identifiers

PMID41055359
PMCPMC12607694

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.