Evidence map›Paper›PMID 41055340›Full record

Trial reportPlastic and reconstructive surgery2026

Efficacy of Nanofat in Wound Healing: A Double-Blinded Randomized Controlled Trial.

Apinut Wongkietkachorn, Nuttapone Wongkietkachorn

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Plastic and reconstructive surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Apinut WongkietkachornFrom the Plastic and Reconstructive Surgery Unit, QPrime Surgical Center.
Nuttapone WongkietkachornFrom the Plastic and Reconstructive Surgery Unit, QPrime Surgical Center.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNanofat has been shown to contain a variety of growth factors, antiinflammatory mediators, and adipose-derived stem cells, all of which may significantly contribute to the wound healing process. However, there is limited comparative clinical evidence supporting its use. This study aims to evaluate the effects of nanofat on wound healing in abdominoplasty by comparing outcomes between nanofat-treated and -nontreated wounds.

methodsA double-blinded randomized controlled trial was conducted using a split-wound model. Each wound was divided and randomized into a nanofat-treated side and a nonnanofat-treated control side. Nanofat was prepared and injected along the wound margins using a standardized dose. Both patients and the surgeons evaluating the wounds were blinded to the treatment allocation. Wound outcomes were assessed 6 months postoperatively using the Observer Scale of the Patient and Observer Scar Assessment Scale.

resultsFifty lipoabdominoplasty patients were included in the study. Wound outcomes were significantly better in the nanofat group compared with the nonnanofat group across all assessed parameters, including vascularity, pigmentation, thickness, relief, pliability, surface area, and overall opinion ( P < 0.001). No oil cysts or fat necrosis were observed in the nanofat group.

conclusionNanofat significantly improved wound outcomes in abdominoplasty patients without associated complications such as oil cysts or fat necrosis.

Indexed as

LipoabdominoplastyWound HealingAdultDouble-Blind MethodFemaleHumansMaleMiddle AgedTreatment Outcome

Identifiers

PMID41055340
PMCPMC13200879

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.