Evidence map›Paper›PMID 41055253›Full record

ArticleAdipocyte2025

A compendium of adipocyte morphologies across different breast pathologies.

Abigail Dodson, Katie Hanna, Kerri Palmer, Hafeez Ibrahim, Katharina Kusserow, Rasha Abu-Eid, Gerald Lip, Nicola Spence, Ehab Husain, Beatrix Elsberger and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Adipocyte, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Abigail DodsonSchool of Medicine, Medical Sciences and Nutrition, Institute of Medical Sciences, Univerisity of Aberdeen, Aberdeen, UK.ORCID 0000-0001-5938-8992
Katie HannaSchool of Medicine, Medical Sciences and Nutrition, Institute of Medical Sciences, Univerisity of Aberdeen, Aberdeen, UK.ORCID 0000-0001-8348-2399
Kerri PalmerSchool of Medicine, Medical Sciences and Nutrition, Institute of Medical Sciences, Univerisity of Aberdeen, Aberdeen, UK.
Hafeez IbrahimSchool of Medicine, Medical Sciences and Nutrition, Institute of Medical Sciences, Univerisity of Aberdeen, Aberdeen, UK.ORCID 0009-0007-4183-1467
Katharina KusserowSchool of Medicine, Medical Sciences and Nutrition, Institute of Medical Sciences, Univerisity of Aberdeen, Aberdeen, UK.ORCID 0000-0002-2818-0838
Rasha Abu-EidSchool of Medicine, Medical Sciences and Nutrition, Institute of Dentistry, University of Aberdeen, Aberdeen, UK.ORCID 0000-0002-6634-0329
Gerald LipBreast Unit, Aberdeen Royal Infirmary, Aberdeen, UK.ORCID 0000-0002-7867-5468
Nicola SpenceBreast Unit, Raigmore Hospital, Inverness, UK.
Ehab HusainBreast Unit, Aberdeen Royal Infirmary, Aberdeen, UK.
Beatrix ElsbergerBreast Unit, Aberdeen Royal Infirmary, Aberdeen, UK.ORCID 0000-0002-2864-5789
Justin J RochfordThe Rowett Institute, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen, UK.ORCID 0000-0002-5020-4939
Valerie SpeirsSchool of Medicine, Medical Sciences and Nutrition, Institute of Medical Sciences, Univerisity of Aberdeen, Aberdeen, UK.ORCID 0000-0002-0602-4666

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adipocytes are abundant in the breast tissue microenvironment. In breast cancer, they can change morphologically according to their proximity to tumour cells, with the closest becoming cancer-associated adipocytes (CAAs). It remains unclear whether breast cancer risk factors, including menopausal status, body mass index (BMI), and mammographic density (MD), influence CAAs morphology in breast carcinogenesis. This study aimed to quantify morphological differences in adipocytes across breast cancer pathologies and associated risk factors. Whole slide images of haematoxylin and eosin stained cancer (

Indexed as

AdipocytesBreastBreast NeoplasmsAdultAgedBody Mass IndexFemaleHumansMiddle AgedRisk FactorsTumor Microenvironmentadipose remodellingAdipose tissue biologybiomarkersfatty acidslipolysis

Identifiers

PMID41055253
PMCPMC12505518

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.