Evidence map›Paper›PMID 41055112›Full record

ArticleOral health & preventive dentistry2025

Effects of Stannous Fluoride Toothpaste and Chios Mastiha Toothpaste on the Prevention of Enamel Erosion.

Konstantina Chatzidimitriou, Spyros Papageorgiou, Sotiria Gizani, William Papaioannou

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Article in Oral health & preventive dentistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Konstantina Chatzidimitriou
Spyros Papageorgiou
Sotiria Gizani
William Papaioannou

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeErosive tooth wear (ETW) is an increasingly prevalent condition characterised by the loss of dental hard tissue due to repeated effects and interactions of acids and mechanical forces. The aim of this study was to investigate the primary preventive effect of salivary pellicle combined with either stannous fluoride (SnF2) toothpaste or mastic toothpaste against ETW in permanent teeth. MATERIALS AND

methodsUsing a three-arm invitro model, 54 enamel samples (18 in each group) were prepared with a salivary pellicle alone (control), salivary pellicle with SnF2 toothpaste, or salivary pellicle with mastic toothpaste. The experimental design consisted of 5 cycles of salivary pellicle formation (30 min, 37°C), modification with the solutions (30 min, 25°C), further salivary pellicle formation (2 h, 37°C) and erosive challenge (2 min, 1% citric acid, pH 3.6). Subsequently, the samples were evaluated by optical profilometry, Vickers hardness (VH), and scanning electron microscopy coupled with energy-dispersive X-ray spectroscopy (SEM/EDX).

resultsSnF₂ group exhibited significantly reduced surface roughness (Sa, Sq, Sc, Sm, Sv parameters) compared to other groups and lower total hardness loss (ΔVH: SnF2 23%, control 26%, mastic 36%) than the mastic group. SEM analysis revealed better preservation of the prismatic enamel structure in the SnF2 group, indicating resistance to acid-induced demineralisation. Mastic toothpaste did not provide significant protection against erosion, raising questions about its suitability for preventing ETW in acidic environments. EDX analysis showed no significant differences in elemental composition among the groups.

conclusionsThis study confirmed the use of SnF2 as an effective agent for protecting enamel against ETW. While natural extracts like mastic may have antimicrobial benefits, their protective role against ETW appears limited, emphasising the need for further research to explore their promising potential applications in oral prevention as well as their limitations. The future of ETW prevention may lie in the synergy between natural and synthetic agents, combining efficacy with biocompatibility and patient acceptance.

Indexed as

Dental EnamelTin FluoridesTooth ErosionToothpastesDental PellicleHardnessHumansMicroscopy, Electron, ScanningSpectrometry, X-Ray EmissionSurface PropertiesTin FluoridesToothpastesdental protectionenamel erosionmasticsalivary pelliclestannous fluoridetoothpaste

Identifiers

PMID41055112
PMCPMC12532033

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.