Evidence map›Paper›PMID 41055017›Full record

ArticleSmall (Weinheim an der Bergstrasse, Germany)2025

Dip-in Nanomechanical Probes for Mass Characterization of Nanoparticles in Ultra-Low Volume Liquid Suspensions.

Juan Molina, Javier E Escobar, Priscila M Kosaka, Óscar Malvar, José J Ruz, Javier Tamayo, Álvaro San Paulo, Montserrat Calleja

Abstract read
In one paragraph

Article in Small (Weinheim an der Bergstrasse, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Juan MolinaInstituto de Micro y Nanotecnología, IMN-CNM, CSIC (CEI UAM+CSIC), Isaac Newton 8, Tres Cantos, Madrid, 28760, Spain.ORCID https://orcid.org/0000-0002-8809-0367
Javier E EscobarInstituto de Micro y Nanotecnología, IMN-CNM, CSIC (CEI UAM+CSIC), Isaac Newton 8, Tres Cantos, Madrid, 28760, Spain.ORCID https://orcid.org/0009-0001-9363-0305
Priscila M KosakaInstituto de Micro y Nanotecnología, IMN-CNM, CSIC (CEI UAM+CSIC), Isaac Newton 8, Tres Cantos, Madrid, 28760, Spain.ORCID https://orcid.org/0000-0003-4242-7064
Óscar MalvarInstituto de Micro y Nanotecnología, IMN-CNM, CSIC (CEI UAM+CSIC), Isaac Newton 8, Tres Cantos, Madrid, 28760, Spain.ORCID https://orcid.org/0000-0001-9860-0634
José J RuzInstituto de Micro y Nanotecnología, IMN-CNM, CSIC (CEI UAM+CSIC), Isaac Newton 8, Tres Cantos, Madrid, 28760, Spain.ORCID https://orcid.org/0000-0003-4604-7042
Javier TamayoInstituto de Micro y Nanotecnología, IMN-CNM, CSIC (CEI UAM+CSIC), Isaac Newton 8, Tres Cantos, Madrid, 28760, Spain.ORCID https://orcid.org/0000-0002-5280-7215
Álvaro San PauloInstituto de Micro y Nanotecnología, IMN-CNM, CSIC (CEI UAM+CSIC), Isaac Newton 8, Tres Cantos, Madrid, 28760, Spain.ORCID https://orcid.org/0000-0001-9325-8892
Montserrat CallejaInstituto de Micro y Nanotecnología, IMN-CNM, CSIC (CEI UAM+CSIC), Isaac Newton 8, Tres Cantos, Madrid, 28760, Spain.ORCID https://orcid.org/0000-0003-2414-5725

Funding

HORIZON EUROPE European Innovation Council 101099058HORIZON EUROPE European Research Council 101157423Ministerio de Ciencia e Innovación 564564
6 · The paper itself

Abstract

The mass of nanoparticles has a critical influence on their phenomenology and functional performance, driving the need for measurement tools that combine high-throughput with high-resolution single-particle analysis. Mass characterization of large nanoparticle populations under such demands remains a persistent challenge, particularly for nanoparticles of large mass, where consolidated techniques encounter limitations. Here, a dip-in nanomechanical probe sensing approach for weighing nanoparticles in liquid suspensions which simultaneously provides high mass resolution and sensing rate is demonstrated. The method relies on nanoparticle transfer to nanowire resonator probes via iterative immersion into the suspension, requiring minimal volume and resulting in negligible losses. It also introduces ionic liquids as suspension media, enabling vacuum operation for optimizing mass resolution through single-mode resonance frequency tracking of the probes. Additionally, implementing acoustofluidic actuation on the suspension regulates nanoparticle adsorption/desorption during immersion, significantly enhancing the sensing rate. Measurements of 30 nm gold nanoparticles demonstrate accurate characterization of their mass distribution with a probe resolution of 0.1 ag, a sensing rate of 38 NPs min

Indexed as

ionic liquidsnanoelectromechanical systems (NEMS)nanomechanical spectrometrynanoparticle characterizationsilicon nanowires

Identifiers

PMID41055017
PMCPMC12658918

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.