Evidence map›Paper›PMID 41054813›Full record

ReviewThe journal of adhesive dentistry2025

Physico-Chemical Properties and Performance of Functional Monomers Used in Contemporary Dental Adhesive Technology.

António H S Delgado, Mohammed H Ahmed, Marta Nunes Ferreira, Ana Mano Azul, Mário Polido, Kumiko Yoshihara, Bart Van Meerbeek

Abstract readReview
In one paragraph

Review in The journal of adhesive dentistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Fracture Resistance of Reattached Tooth Fragments: Influence of Adhesive Curing Mode and Composite Viscosity.Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

António H S Delgado
Mohammed H Ahmed
Marta Nunes Ferreira
Ana Mano Azul
Mário Polido
Kumiko Yoshihara
Bart Van Meerbeek

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This comprehensive literature-based review critically examines the physico-chemical properties of functional monomers present in contemporary dental adhesive formulations or dental materials relying on self-adhesive technology. A qualitative synthesis of evidence was conducted through searches in PubMed, Scopus, and LILACS over a 20-year period (2005-2025), without language restrictions. Data on the chemical structure, composition, adhesive performance, pKa, etching efficacy, polymerization, mechanical properties, toxicity, and hydrolytic stability/degradation were analyzed from peer-reviewed studies and manufacturer technical information. Several relevant acidic functional monomers are covered, but key players include 10-MDP, GPDM, and 4-META. Notably, 10-MDP emerged as the most prevalent monomer in commercial adhesives, appearing in nearly 50% of the current adhesives in the market. Its superior adhesive performance and longevity stem from its unique chemical characteristics, whereas other commercial acidic monomers, including GPDM and 4-META, are still present in many adhesive formulations despite their structural limitations and comparatively lower bonding efficacy. Understanding the chemical composition of dental adhesives is essential for achieving improved clinical outcomes and driving material development. This knowledge allows clinicians to select adhesive materials based on performance requirements and informs future innovations to address challenges such as degradation pathways, biocompatibility, and their overall long-term bonding efficacy.

Indexed as

Dental CementsTechnology, DentalChemical PhenomenaDental BondingHumansMaterials TestingMethacrylatesPolymerizationDental CementsMethacrylates10-MDPadhesion in dentistrydental adhesionetchingfunctional monomerhybrid layermonomerself-adhesiveself-etching adhesiveself-etching systemuniversal adhesive

Identifiers

PMID41054813
PMCPMC12532035

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.