Evidence map›Paper›PMID 41054660›Full record

ArticleCureus2025

Successful Treatment of Disseminated Carcinomatosis of the Bone Marrow Secondary to Colorectal Cancer With Modified FOLFOX6 Plus Panitumumab: A Case Report.

Junsei Noda, Akinori Sasaki, Risa Okamoto

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Junsei NodaGastroenterology, Tokyo Bay Urayasu Ichikawa Medical Center, Urayasu, JPN.
Akinori SasakiGastroenterology, Tokyo Bay Urayasu Ichikawa Medical Center, Urayasu, JPN.
Risa OkamotoGastroenterology, Tokyo Bay Urayasu Ichikawa Medical Center, Urayasu, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Disseminated carcinomatosis of the bone marrow (DCBM) is a rare, aggressive manifestation of colorectal cancer (CRC). It is often accompanied by pancytopenia and disseminated intravascular coagulation (DIC) and has a poor prognosis. Herein, we present the case of a 61-year-old male patient with sigmoid colon cancer and DCBM who presented with fever, fatigue, and DIC. Bone marrow biopsy confirmed poorly differentiated adenocarcinoma, consistent with the primary tumor. Genetic testing revealed the RAS and BRAF wild-type status. The patient was administered modified FOLFOX6 plus panitumumab as first-line chemotherapy. The patient's clinical symptoms improved rapidly, and transfusion dependency resolved after two cycles of chemotherapy. Subsequent comprehensive genomic profiling identified a subclonal

Indexed as

colorectal cancerdisseminated carcinomatosis of the bone marrowdisseminated intravascular coagulationfolfoxpanitumumab

Identifiers

PMID41054660
PMCPMC12497423

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.