Evidence map›Paper›PMID 41054647›Full record

ArticleCureus2025

Magnitude and Determinants of Dry Eye Syndrome Among Persons With Diabetes Mellitus.

Leema Alhussayen, Amna M Alshenqeti, Raghad Alfaqi, Waseem A Aalam

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Leema AlhussayenInternal Medicine, King Salman Bin Abdulaziz Medical City, Madinah, SAU.
Amna M AlshenqetiFamily Medicine, Prince Sultan Military Medical City, Riyadh, SAU.
Raghad AlfaqiDepartment of Infectious Diseases, King Abdulaziz Medical City Riyadh, Jeddah, SAU.
Waseem A AalamOphthalmology, University of Jeddah, Jeddah, SAU.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo present the prevalence and determinants of dry eye syndrome (DES) among adult Saudi persons with diabetes at a diabetes centre in central Saudi Arabia.

methodThis cross-sectional study included diabetic patients attending a diabetic centre in 2018. The status of DES was based on the Ocular Surface Disease Index (OSDI) questionnaire. The prevalence of DES among patients with diabetes was estimated. The demographic and diabetes status were correlated with the OSDI score.  Results: The DES was found in 237 of 276 persons with a prevalence of 85.9% (95% Confidence Interval 81.8; 90.0). The median OSDI score was 37.5 (Interquartile range (IQR) 20.8; 50). The median hemoglobin A1c (HbA1c) level was 8.6 Mmol/mol (IQR, 7.7-9.7). The OSDI score was not significantly correlated with HbA1C level (Spearman r = 0.794). Age (P = 0.42), gender (P = 0.81), duration of diabetes (P = 0.1), smoking (P = 0.5), contact lens usage (P = 0.36), refractive surgery (P = 0.17), and allergy (P = 0.42) were not significantly associated with OSDI score. Those using insulin for diabetes had a significantly higher OSDI score than those using a type of hypoglycemic medication (P = 0.029). The coverage for care for DES among persons with diabetes was 32.1% only.

conclusionThe prevalence of DES was high among persons with diabetes. DES was not correlated with duration of diabetes, age, or other known risk factors for DES. Diabetic insulin users diabetic patients had a higher grade of DES compared to those controlling diabetes with oral hypoglycemic medications. Eye care for individuals with diabetes and DES is recommended.

Indexed as

diabetes mellitusdry eye diseasedry eye syndromeglycaemic controlocular surface disease index

Identifiers

PMID41054647
PMCPMC12497496

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.