Evidence map›Paper›PMID 41054646›Full record

ArticleCureus2025

Intractable Neuromuscular Blockade Resistant to Sugammadex Rescue Administration: A Case Report.

Vinh T Nguyen, Jason Cosman, Govind Rajan

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Vinh T NguyenSchool of Medicine, California University of Science and Medicine, Colton, USA.
Jason CosmanAnesthesiology and Perioperative Medicine, University of California, Irvine (UCI) Health, Orange, USA.
Govind RajanAnesthesiology and Perioperative Medicine, University of California, Irvine (UCI) Health, Orange, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We describe the failure of sugammadex when used as a rescue agent, after neuromuscular blockade with rocuronium was insufficiently reversed with neostigmine and glycopyrrolate. Despite repeated doses, this patient needed to be reintubated and sedated until spontaneous recovery was observed over the next few hours. With the increasing preference to utilize sugammadex in the perioperative setting, we are starting to notice a significant number of patients displaying residual paralysis despite sugammadex administration as a solo or rescue agent at our institution. We believe that more attention is needed to examine the factors that contribute to insufficient neuromuscular blockade reversal in these settings.

Indexed as

paralysis (chemically induced)recurarizationresidual neuromuscular blockaderocuroniumsugammadex

Identifiers

PMID41054646
PMCPMC12497430

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.