Evidence map›Paper›PMID 41054562›Full record

ArticleInternational journal of general medicine2025

Serum Metallome Features and Their Effects on Chronic Kidney Disease: A Comparative Study.

Jiuyi Jiang, Lingxiao Hu, Chunmei Dai, Bin Zhang, Xi Chen, Yuwei Yang, Jiafu Feng

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of general medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jiuyi Jiang *Department of Medical Laboratory, The Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan, 646000, People's Republic of China.
Lingxiao Hu *Department of Medical Laboratory, The Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan, 646000, People's Republic of China.
Chunmei DaiDepartment of Medical Laboratory, The Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan, 646000, People's Republic of China.
Bin ZhangDepartment of Medical Laboratory, The Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan, 646000, People's Republic of China.
Xi ChenDepartment of Clinical Laboratory, Mianyang Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Mianyang, Sichuan, 621000, People's Republic of China.
Yuwei YangDepartment of Clinical Laboratory, Mianyang Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Mianyang, Sichuan, 621000, People's Republic of China.ORCID 0000-0002-0908-1228
Jiafu FengDepartment of Medical Laboratory, The Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan, 646000, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Epidemiological evidence links exposure to certain metals with decreased kidney function and kidney disease progression. This study investigates the metallome profiles in chronic kidney disease (CKD) patients and their relationship to disease onset and progression. Methods: A total of 341 CKD patients (CKD group) and 60 healthy controls (HC group) were recruited. Renal function markers, including urea, creatinine (Creat), uric acid (UA), cystatin C (CysC), and complement component 1q (C1q), along with the levels of 26 metal elements, were assessed to examine the relationship between metal element concentrations and renal function markers. Results: Compared to the HC group, serum concentrations of Li, Mg, Al, Ca, V, Mn, Ni, Cu, Ga, Se, Rb, Mo, Sn, Cs, and Pb were elevated in CKD patients (all Conclusion: CKD patients exhibit altered serum levels of various metals. Al, V, Co, Ga, Cs, and Pb are linked to CKD onset, while Li, V, Mo, and Cs relate to its progression. These findings suggest that monitoring specific metal elements like V, Pb and Mo could aid in early CKD detection and progression assessment.

Indexed as

chronic kidney diseasemetabolic profilesmetallomeultra-high performance liquid chromatography-tandem mass spectrometry

Identifiers

PMID41054562
PMCPMC12497381

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.