ArticleEpidemiology and infection2025
Tracking the evolutionary footprint of Mpox in West Africa: phylogenetic and clade analysis.
Article in Epidemiology and infection, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Severe Mpox and Uncontrolled HIV Co-Infection in Lagos, Nigeria - A Case Report.Nigerian medical journal : journal of the Nigeria Medical AssociationReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mpox (formerly called monkeypox) is a zoonotic viral disease caused by the monkeypox virus (MPXV) that has recently emerged as a notable global health issue by spreading beyond its typical geographical zones in Central and West Africa. In this study, we conducted a phylogenetic and evolutionary investigation of MPXV in West Africa. We focussed on 167 complete genome sequences collected from human infections in Nigeria and Cameroon between 2019 and 2024, all of which were retrieved from the GSAID database. To analyse these sequences, we employed multiple sequence alignment using fast Fourier transform (MAFFT) and maximum likelihood techniques to identify conserved genomic variants and trace evolutionary patterns within the virus. Our findings revealed that all the MPXV strains studied belong to clade II, which is further subdivided into two subclades. Notably, this study documents the presence of two distinct subclades IIa and IIb, reflecting the complex and ongoing evolution of the virus in the region. The phylogenetic analysis reveals rapid mutations and suggests that MPXV is being transmitted from multiple lineages between Nigeria and Cameroon. This demands the need to further strengthen the surveillance and containment efforts in West Africa. This study highlights the role of genomic surveillance in monitoring the evolution and spread of the MPXV, particularly in regions with limited available data.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.