Evidence map›Paper›PMID 41053951›Full record

ArticleChemistryOpen2025

Preparation of Hierarchically Structured Perlite NPs/Metformin-Co (II) System to Catalyze the Green Synthesis of Pyrazolopyranopyrimidines.

Jalal Reihani Shurbakhlu, Leila Moradi, Abdulhamid Dehghani

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ChemistryOpen, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jalal Reihani ShurbakhluDepartment of Organic Chemistry, Faculty of Chemistry, University of Kashan, Kashan, P.O. Box 87317-51167, Iran.
Leila MoradiDepartment of Organic Chemistry, Faculty of Chemistry, University of Kashan, Kashan, P.O. Box 87317-51167, Iran.ORCID https://orcid.org/0000-0001-8795-0954
Abdulhamid DehghaniDepartment of Organic Chemistry, Faculty of Chemistry, University of Kashan, Kashan, P.O. Box 87317-51167, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study presents an innovative heterogeneous nanocatalytic system designed through a multistep synthetic approach involving the surface functionalization of perlite nanoparticles (Perlite NPs/Met-Co(II)). Comprehensive characterization using fourier transform infrared spectroscopy (FTIR), X-ray diffraction, field-emission scanning electron microscopy, energy-dispersive X-ray analysis (EDX), elemental mapping, thermogravimetric analysis, and brunauer-emmett-teller (BET) analyses confirms the successful formation of a hierarchically structured catalyst. The catalyst enables efficient one-pot multicomponent synthesis of pyrazolopyranopyrimidines in water (100 °C, 5 mg loading), yielding 87-95% in 30-60 min. The presented method adhering to green principles and also recyclability (6 cycles) and synergistic performance provides an atom-economic platform for sustainable heterocycle synthesis.

Indexed as

green chemistryheterogeneous catalystmulticomponent reactionperlite nPs/Met‐co(II)pyrazolopyranopyrimidine

Identifiers

PMID41053951
PMCPMC12680556

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.