Multiple physiological and behavioural parameters identification for dietary monitoring using wearable sensors: a study protocol.

introductionTraditional dietary intake assessment is labour- and time-consuming and prone to inaccuracies and biases. Emerging wearable sensing technology may offer a promising solution. This protocol paper describes a study investigating the physiological responses to energy intake utilising a customised wearable multi-sensor band, which is specifically designed to monitor multiple physiological and behavioural responses related to eating and digestion events for dietary monitoring. METHODS AND ANALYSIS: This study will recruit 10 healthy volunteers from databases and public advertisements, with informed consent required prior to participation. Participants will attend two main study visits at a clinical research facility, consuming pre-defined high- and low-calorie meals in a randomised order. Wearable sensors will be worn throughout the eating episodes to track hand-to-mouth movements and physiological changes, including skin temperature (Tsk), heart rate (HR), and oxygen saturation (SpO ETHICS AND DISSEMINATION: Ethical approval has been granted by London - Westminster Research Ethics Committee. REC reference: 23/PR/1379. Written informed consent will be obtained from all participants. Findings will be disseminated through peer-reviewed journals, conferences, and seminar presentations. Protocol V.5. Protocol date: 16 January 2024. TRIAL REGISTRATION NUMBER: NCT06398340 in ClinicalTrials.gov, registration date 03 May 2024.