ReviewStem cell research & therapy2025
The regenerative journey: exploring stem cell roles from injury detection to tissue repair.
Review in Stem cell research & therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Nanofiber-reinforced ECM-based bioink for hybrid biofabrication of adventitia-mimetic anisotropic vascular constructs.Stem cell research & therapy · 2026Article
- Comparative Wound Healing Processes in Plants and Animals: Bioinspired Strategies for Advancing Regenerative Medicine.International journal of molecular sciences · 2026Review
- The E-cadherin-Wnt-mir-994 Axis Repurposes a Cadherin Switch for Niche Robustness and Germline Stem Cell Maintenance.Cell proliferation · 2026Article
- Coriander Honey Accelerates Human Osteoblast Differentiation and Matrix Mineralization via Intracellular CaPharmaceuticals (Basel, Switzerland) · 2026Article
- Stem Cells in Cosmetic Applications: Advancements, Challenges, and Future Directions.Journal of cosmetic dermatology · 2026Review
- Repair and regeneration across the lifespan: an ontogenetic perspective.Frontiers in aging · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
The intricate process of tissue regeneration, driven by endogenous mechanisms, represents a sophisticated interplay of biological events from injury detection to functional recovery. This review discusses the multifaceted journey of stem cells in response to physiological and pathological cues. Beginning with detecting tissue damage through biochemical signals, the subsequent acute inflammatory response activates stem cells residing in specialized niches. These cells are then recruited to the injury site via chemotactic gradients of growth factors and cytokines. Once localized, stem cells proliferate and differentiate, influenced by the local microenvironment, which provides essential cues for their fate decisions. Integrating newly formed cells into the tissue matrix, supported by modulation of inflammation, angiogenesis, and extracellular matrix remodelling, is crucial for restoring tissue architecture and function. By exploring these biological details and leveraging advancements in medical technology, this review aims to enhance the understanding of regenerative therapies, offering new avenues for effective tissue repair and recovery.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.