Evidence map›Paper›PMID 41053827›Full record

SynthesisSystematic reviews2025

Effects of combined transcranial direct current stimulation and gait training in Parkinson's disease: a systematic review and meta-analysis of randomized controlled trials.

Shutao Qiu, Yixin Wei, Chaoran Gao, Xiangxiang Zhang, Qiang Gao

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Systematic reviews, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shutao Qiu *Rehabilitation Medicine Centerand, Institute of Rehabilitation Medicine , West China Hospital, Sichuan University, Chengdu, 610041, China.ORCID 0009-0003-2645-5820
Yixin Wei *Rehabilitation Medicine Centerand, Institute of Rehabilitation Medicine , West China Hospital, Sichuan University, Chengdu, 610041, China.ORCID 0009-0002-0637-6933
Chaoran GaoRehabilitation Medicine Centerand, Institute of Rehabilitation Medicine , West China Hospital, Sichuan University, Chengdu, 610041, China.
Xiangxiang ZhangRehabilitation Medicine Centerand, Institute of Rehabilitation Medicine , West China Hospital, Sichuan University, Chengdu, 610041, China.
Qiang GaoRehabilitation Medicine Centerand, Institute of Rehabilitation Medicine , West China Hospital, Sichuan University, Chengdu, 610041, China. gaoqiang_hxkf@163.com.ORCID 0000-0003-3603-749X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundParkinson's disease (PD) is the second most common neurodegenerative disorder worldwide. Transcranial direct current stimulation (tDCS) and gait training have been demonstrated as effective treatments for patients with PD. However, the effects of combined tDCS and gait training on PD remain unclear. This systematic review and meta-analysis aimed to evaluate the effects of combined tDCS and gait training in PD patients.

methodsWe conducted literature searches in EMBASE, PubMed, Web of Science, Cochrane Library, the Chinese National Knowledge Infrastructure databases, VIP, Wanfang, SinoMed, and the Chinese Medical Association Journal Database to identify the effects of combined transcranial direct current stimulation and gait training in PD patients.

resultsEight randomized controlled trials with a total of 183 PD patients were analyzed. Statistically significant improvements were observed only in double support time, both immediately after intervention (MD = 0.04, 95% CI, 0.02 to 0.06, I

conclusionstDCS combined with gait training compared with gait training alone did not make a statistically significant improvement in efficacy in patients with PD.

Indexed as

Exercise TherapyGaitParkinson DiseaseTranscranial Direct Current StimulationHumansRandomized Controlled Trials as TopicGait trainingMeta-analysisParkinson’s diseaseTranscranial direct current stimulation

Identifiers

PMID41053827
PMCPMC12502194

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.