Evidence map›Paper›PMID 41053726›Full record

ReviewBiomedical engineering online2025

Applications of recombinant type III collagen in tissue engineering.

Yuchen Shan, Ting Wang, Haiyan Lin

Abstract readReview
In one paragraph

Review in Biomedical engineering online, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yuchen ShanSchool of Stomatology, Zhejiang Chinese Medical University, Hangzhou, China.
Ting WangDepartment of Oral and Maxillofacial Surgery, Leiden University Medical Center (LUMC), Leiden, 2333 ZA, The Netherlands.
Haiyan LinSavid School of Stomatology, Hangzhou Medical College, No.8, Yikang Street, Hangzhou, 311399, Zhejiang, China. lhaiyanlily@163.com.

Funding

China Scholarship Council No. 202308330121Key Research and Development Plan of Zhejiang Province No. 2023C03070
6 · The paper itself

Abstract

Recombinant human type III collagen (rhCol III) is a promising biomaterial for tissue engineering due to its excellent biocompatibility and bioactivity. This review summarizes the structure, development, and applications of rhCol III in bone and soft tissue engineering. Advances in genetic engineering have enabled the production of rhCol III with customizable properties. It plays a key role in promoting tissue repair and regeneration, with significant potential in wound healing, skin repair, and anti-inflammatory responses. However, challenges remain in optimizing its mechanical properties for specific applications. Future research should focus on improving production efficiency and clinical translation while addressing potential host responses.

Indexed as

Collagen Type IIITissue EngineeringAnimalsBiocompatible MaterialsHumansRecombinant ProteinsWound HealingBiocompatible MaterialsCollagen Type IIIRecombinant ProteinsBiomaterialsCollagenExtracellular matrixRecombinant human type III collagenrhCol IIITissue engineering

Identifiers

PMID41053726
PMCPMC12502140

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.