Trial reportBMC oral health2025
Analysis of the factors influencing the occurrence of peri-implantitis in patients with implant-supported restoration and study on the maintenance effect of subgingival sandblasting.
Trial report in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06998160 (Changsha Stomatological Hospital), which is not on this map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Changsha Stomatological Hospital
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
objectiveThis study aims to identify risk factors for peri-implantitis in patients with implant-supported restoration, and explore the efficacy of subgingival sandblasting in modulating peri-implant microecology, so as to provide a basis for optimizing clinical management.
methodsNinety-six patients with early peri-implantitis treated from July 2022 to July 2024 were enrolled as the inflammation group and randomly subdivided into control, glycine-based subgingival sandblasting, and erythritol-based subgingival sandblasting groups (n = 32/group). Clinical outcomes were compared. Additionally, 102 patients without inflammation post-implant-supported restoration were selected as the non-inflammation group for independent risk factor analysis.
resultsUnivariate analysis showed that peri-implantitis was related to 9 factors such as lower educational level, smoking, and diabetes (P < 0.05). Multivariate analysis further confirmed higher educational level (OR = 0.408) and regular dental cleaning (OR = 0.34) as protective factors, while implant sevice time ≥ 5 years (OR = 4.614) and insufficient keratinized mucosa width (OR = 3.267) as independent risk factors (all P < 0.05). Subgingival sandblasting (glycine/erythritol) significantly reduced plaque index (PLI), bleeding index (BI), and inflammatory factors (IL-6, IL-1β; P < 0.05). The erythritol group demonstrated superior long-term anti-inflammatory efficacy (e.g., IL-1β: 4.43 versus glycine 6.02 at 6 months; P < 0.001), though probing depth (PD) improvements attenuated beyond 6 months. Both subgingival sandblasting groups reported significantly higher patient satisfaction scores for aesthetic appearance and functional characteristics than controls (P < 0.05).
conclusionPeri-implantitis arises from interactions among oral hygiene, anatomical factors, and systemic conditions. Subgingival sandblasting effectively controls peri-implantitis progression by disrupting plaque biofilm and suppressing inflammation, with erythritol offering extended anti-inflammatory benefits. Sustained clinical outcomes needs adjunctive maintenance therapy alongside subgingival sandblasting. CLINICALTRIALS.GOV IDENTIFIER: NCT06998160(25th/April/2025) https://register.clinicaltrials.gov/prs/beta/records
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.