Evidence map›Paper›PMID 41053697›Full record

ReviewBMC biology2025

Bending the rules: curvature's impact on cell biology.

Carole Arnold, Ismail Tahmaz, Marie-Ly Chapon, Hasna Maayouf, Valeriy Luchnikov, Jean-Louis Milan, Fabricio Borghi, Laurent Pieuchot

Abstract readReview
In one paragraph

Review in BMC biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Carole ArnoldIS2M (CNRS - UMR 7361), Université de Haute-Alsace, 68100, Mulhouse, France. carole.arnold@uha.fr.
Ismail TahmazIS2M (CNRS - UMR 7361), Université de Haute-Alsace, 68100, Mulhouse, France.
Marie-Ly ChaponIS2M (CNRS - UMR 7361), Université de Haute-Alsace, 68100, Mulhouse, France.
Hasna MaayoufIS2M (CNRS - UMR 7361), Université de Haute-Alsace, 68100, Mulhouse, France.
Valeriy LuchnikovIS2M (CNRS - UMR 7361), Université de Haute-Alsace, 68100, Mulhouse, France.
Jean-Louis MilanUniv Gustave Eiffel, Aix Marseille Univ, LBA, 13016, Marseille, France.
Fabricio BorghiInstituto de Fisica, Universidade Federal Do Rio de Janeiro, Rio de Janeiro, 21941-611, Brazil.
Laurent PieuchotIS2M (CNRS - UMR 7361), Université de Haute-Alsace, 68100, Mulhouse, France. laurent.pieuchot@uha.fr.

Funding

SPERMIDINE DERIVATIVES AS POTENTIAL ANTICANCER AGENTSR01CA022153 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI PORTER, CARL W · 1985 to 2007
$2.6M
Agence Nationale de la Recherche ANR MovingCells 2-CE45-0010Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - Brasil (CAPES) Finance Code 001NCI NIH HHS R01 CA022153
6 · The paper itself

Abstract

Curvature is a ubiquitous feature in biology, shaping structures at every scale and playing diverse roles in processes ranging from membrane dynamics to tissue organization. In this review, we first introduce briefly the fundamental concepts and mathematical principles of curvature. The second section explores how membrane curvature is perceived by molecular sensors and integrated into cellular responses. The third section examines the effects of curvature on cellular processes and behaviors at the cell-scale, providing a detailed discussion of the underlying mechanisms. Finally, we offer insights into emerging perspectives and highlight the future challenges in unraveling the multifaceted roles of curvature in biology.

Indexed as

Cell BiologyCell MembraneAnimalsHumansModels, BiologicalCell migrationCurvatureCurvotaxisMechanosensingSubstrate topography

Identifiers

PMID41053697
PMCPMC12502368

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.