Evidence map›Paper›PMID 41053661›Full record

ArticleBMC ophthalmology2025

Halo sign in keratoconus: a case report.

Hui He, Lijun Qu

Abstract readCase Reports
In one paragraph

Article in BMC ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Hui HeDepartment of Ophthalmology, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Lijun QuDepartment of Ophthalmology, The Second Affiliated Hospital of Harbin Medical University, Harbin, China. qulijun@hrbmu.edu.cn.

Funding

Beijing medical award foundation YXJL-2021-0815-0547
6 · The paper itself

Abstract

backgroundThere are several clinical signs that may contribute to the diagnosis of keratoconus. Their appearance is associated with the evolution of keratoconus. In this case, the formation of a halo on the iris in a patient with stage IV keratoconus was reported. This halo sigh is a novel one and has not been reported earlier. CASE PRESENTATION: A 30-year-old woman presented to the ophthalmology clinic with one year history of vision deterioration to finger counting in her left eye. A diagnosis of keratoconus was made due to the inferior-central corneal steepening and thinning. When the slit-lamp light projects onto the cone, a halo forms on the iris and shifts its shape and location as the irradiation angle changes.

conclusionA halo sign was observed on the iris of a patient with stage IV keratoconus (Amsler-Krumeich classification) when the slit-lamp beam was projected onto the corneal cone.

Indexed as

IrisKeratoconusAdultCorneal TopographyFemaleHumansSlit Lamp MicroscopyVisual AcuityCorneaHalo signKeratoconusOptometry

Identifiers

PMID41053661
PMCPMC12502615

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.