ArticleBMC pregnancy and childbirth2025
Gestational diabetes mellitus and risk of type 2 diabetes 4 years after the index pregnancy in Moroccan women-a prospective cohort study.
Article in BMC pregnancy and childbirth, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Association between pregnancy cumulative glycemic exposure and postpartum glucose metabolism outcomes at 4-7 years: a cohort study.Frontiers in medicine · 2026Article
- GDM as a unique pathophysiological entity or a transitional pregnancy-induced glucose metabolism abnormality identifying primary diabetes types?Frontiers in physiology · 2026Review
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5 authors.
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Abstract
backgroundThe epidemic of diabetes mellitus is spreading throughout the world. Gestational diabetes mellitus (GDM), a transitory form of diabetes first recognized during pregnancy, is a known harbinger of future type 2 diabetes mellitus (T2DM), hypertension, and cardiac disease. To prevent the future onset of T2DM in mothers and offspring, preventive postpartum care and follow-up are necessary. However, the area remains grossly underprioritized. This study aims to examine long-term metabolic changes, including T2DM, in a cohort of Moroccan women with a known history of GDM.
methodsA prospective cohort study was conducted in the Marrakech-Safi region in Morocco. Women with GDM (initial cohort, n = 210) and those who did not develop hyperglycemia (non-GDM) during 2016-2017 were examined in 2020-2021. Women were classified by a 2-h, 75-g oral glucose tolerance test according to the World Health Organization criteria. Historical data from the index pregnancy and anthropometrical measurements were collected.
resultsThe median duration of follow-up was 4.00 years. Although our study population was relatively young (mean age 31.1 years), a woman with GDM in the index pregnancy was 3.15 (adjusted OR 3.15; 95% CI 1.25-7.52) times more likely to develop T2DM within 4 years than women with no GDM after controlling for other confounding variables. Women with obesity (BMI ≥ 30 kg/m
conclusionGiven the emerging burden of GDM and the steady increase in diabetes-related morbidity and mortality rates, there is a pressing need to transform the current maternal and child health system to address a burgeoning metabolic challenge for this high-risk population in Morocco. Initiating interventions during preconception and continuing into the postpartum period has the potential to confer long-term maternal-child benefits, promoting virtuous cycles of health.
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