ArticleScientific reports2025
Combined antibacterial effect of essential oils from three Indian medicinal plants and antibiotic tetracycline on MRSA using simplex centroid mixture design.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
- Current Knowledge of the GenusPharmaceuticals (Basel, Switzerland) · 2026Review
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3 authors.
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Abstract
Methicillin-resistant Staphylococcus aureus (MRSA) is a major global pathogen, recognized for its high level of antimicrobial resistance. Essential oils have been extensively studied in both observational and clinical research for their promising antimicrobial properties. This study aimed to characterize the essential oils Satureja montana (SMEO), Syncarpia glomerulifera (SGEO), and Valeriana officinalis (VOEO) using GC-MS analysis and their synergistic antibacterial activity in combination with tetracycline evaluated through an augmented simplex centroid mixture design. Mixture design is a statistical phenomenon which is applied to obtain the maximum desired outcomes through minimizing number of experiments. GC-MS identified major components such as benzene, 4-ethyl-1,2-dimethyl (15.70%) in SMEO, copaene (20.95%) in SGEO, and β-maaliene (12.19%) in VOEO. SMEO exhibited the highest antioxidant activity (IC
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