Evidence map›Paper›PMID 41053317›Full record

Trial reportJournal of perinatology : official journal of the California Perinatal Association2026

Multisensory stimulation by mothers: impact on neonatal pain and maternal anxiety during heel blood collection: a randomized controlled trial.

Ayşenur Akkaya-Gül, Nurcan Özyazıcıoğlu, Ezgi Çelikboya-Kabadayı

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Journal of perinatology : official journal of the California Perinatal Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05606458 (The Effect of Multisensory Stimulation Applied by the Mother to Her Infant During the Heel Blood Collection Procedure on the Infant's Pain and Mother's State Anxiety), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05606458 nacompletednot on this map

The Effect of Multisensory Stimulation Applied by the Mother to Her Infant During the Heel Blood Collection Procedure on the Infant's Pain and Mother's State Anxiety: A Randomized Controlled Trial

TypeinterventionalSponsorUludag UniversityRan2019 to 2020Enrolled80ConditionsPainArmsİntervention Group
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ayşenur Akkaya-GülDepartment of Child Health and Diseases Nursing, Health Sciences Institute, Bursa Uludağ University, Bursa, Turkey. aysenurakkaya006@gmail.com.ORCID http://orcid.org/0000-0001-9019-8740
Nurcan ÖzyazıcıoğluDepartment of Child Health and Diseases Nursing, Faculty of Health Sciences, Bursa Uludağ University, Bursa, Turkey.ORCID http://orcid.org/0000-0001-9645-7221
Ezgi Çelikboya-KabadayıDepartment of Child Health and Diseases, Department of Pediatric Intensive Care, Marmara University Pendik Training and Research Hospital, Istanbul, Turkey.ORCID http://orcid.org/0000-0001-7485-9326

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to evaluate the effects of maternal multisensory stimulation on neonatal pain and maternal state anxiety during heel blood collection in neonates. STUDY

designA randomized controlled trial was conducted from July 2019 to January 2020 in neonatal units, with 80 newborns in intervention(n = 40) and control (n = 40) groups. In the intervention group, mothers provided multisensory stimulation (speech, touch, skin odor, breastfeeding, eye contact), while the control group received routine care. Neonatal Infant Pain Scale (NIPS) and maternal state anxiety inventory were evaluated.

resultsNIPS scores and maternal anxiety were significantly lower in the intervention group (p < 0.001). A positive correlation was found between NIPS and maternal anxiety in the intervention group (r = 0.372, p = 0.018).

conclusionsMaternal multisensory stimulation reduces neonatal pain and maternal anxiety. These findings emphasize the importance of pediatric nurses considering neonatal comfort and maternal emotional well-being during medical procedures. CLINICAL

trial registrationThe protocol for this randomized controlled experimental trial is registered on ClinicalTrials.gov. The clinical trial registration number is https://clinicaltrials.gov ; NCT05606458.

Indexed as

AnxietyBlood Specimen CollectionMothersPainPain ManagementPhlebotomyProcedural PainAdultFemaleHeelHumansInfant, NewbornMalePain Measurement

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.