ArticleTranslational psychiatry2025
Integrating cellular and soluble immune signatures of major depression with and without recent suicide attempts.
Article in Translational psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Elucidating Immune Cell Mediated Causal Pathways Linking Blood Metabolites to Major Depressive Disorder: A Mediation Mendelian Randomization Analysis.Brain and behavior · 2026Article
- Sigma-1R-CD36 axis in myeloid cells contributes to the alleviation of depression-like behaviors.Journal of translational medicine · 2026Article
- Recent advances in biomarkers for cardiac fibrosis.Frontiers in cardiovascular medicine · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
Suicide attempts (SA) during major depressive episodes (MDE) pose a significant clinical challenge, yet its underlying biological mechanisms, particularly those associated with recent SA, remain poorly understood. In this case-control study (n = 106), we compared the immunological profiles associated with MDE without SA (n = 36), MDE with a recent SA (n = 35), and a healthy controls (n = 35). Fresh blood samples were analyzed for total cell count and using flow cytometry (FACS) to assess specific cell surface markers. Plasma proteins were quantified using multiplex ELISA or Quanterix. Multiple factorial analysis (MFA) identified three primary dimensions structuring the biological markers: soluble immune and growth factors, cellular immunity (cell ratios, CD45
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.