Evidence map›Paper›PMID 41053096›Full record

ArticleScientific reports2025

Changes in electrical vectors correlated with coronary insufficiency with recent symptoms.

Cameruddin W Vellani, Abdul Hakeem, Satwat Hashmi, Mehwish Shehzad, Hira Mehtab, Sehrish Karim, Osman Faheem, Safia Awan, Zainab Samad

Abstract read
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In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Cameruddin W VellaniDepartment of Medicine, The Aga Khan University, Stadium Road, P.O. Box 3500, Karachi, 74800, Pakistan. camer.vellani@aku.edu.
Abdul HakeemNational Institute of Cardiovascular Diseases Karachi Cantonment, Karachi, 75510, Pakistan.
Satwat HashmiDepartment of Biological and Biomedical Sciences, The Aga Khan University, Stadium Road, P.O. Box 3500, Karachi, 74800, Pakistan. satwat.hashmi@aku.edu.
Mehwish ShehzadDepartment of Medicine, The Aga Khan University, Stadium Road, P.O. Box 3500, Karachi, 74800, Pakistan.
Hira MehtabDepartment of Medicine, The Aga Khan University, Stadium Road, P.O. Box 3500, Karachi, 74800, Pakistan.
Sehrish KarimDepartment of Medicine, The Aga Khan University, Stadium Road, P.O. Box 3500, Karachi, 74800, Pakistan.
Osman FaheemDepartment of Medicine, The Aga Khan University, Stadium Road, P.O. Box 3500, Karachi, 74800, Pakistan.
Safia AwanDepartment of Medicine, The Aga Khan University, Stadium Road, P.O. Box 3500, Karachi, 74800, Pakistan.
Zainab SamadDepartment of Medicine, The Aga Khan University, Stadium Road, P.O. Box 3500, Karachi, 74800, Pakistan.

Funding

Department of Medicine, Aga Khan University AKU ERC 2023-8354-25934
6 · The paper itself

Abstract

Vectorcardiography (VCG) enables measurement of voltages and directions of resultant spatial vectors in the heart that are altered by myocardial ischemia. To validate the ability of VCG to detect electrophysiological effects of regional myocardial ischemia and identify blood vessels that obstruct blood flow significantly, VCG records of 37 patients who presented with unstable symptoms of ischemia requiring coronary angiography (CA) were processed and analyzed. The difference in magnitude and direction of electrical vectors were measured before and after percutaneous coronary intervention (PCI) to study the significance of changes after revascularization. Bio amplifiers recorded 3 simultaneous orthogonal lead ECG signals with low-pass frequency of 150 Hz without electronic filtration. The analogue signals were digitized and recorded for analysis. The numerical output was processed by algorithms to calculate and display the state of vectors. 36 of 37 patients showed congruence between VCG and CA results: 34 of the 36 showed changes in electrical vectors and insufficient blood supply. 2 showed no changes in electrical vectors and non-obstructive arteries on CA. 1 patient had ischemia detected by VCG, but CA was negative. Blood vessels that were opened with PCI corresponded with regions of myocardial ischemia and expected coronary blood supply on VCG interpretation.

Indexed as

Myocardial IschemiaVectorcardiographyAgedAlgorithmsCoronary AngiographyElectrocardiographyFemaleHumansMaleMiddle AgedPercutaneous Coronary InterventionCoronary angiographyElectrophysiology.Myocardial ischemiaPercutaneous coronary interventionVectorcardiography

Identifiers

PMID41053096
PMCPMC12500967

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.