ArticleNature communications2025
Sustainable recycling of polyamides via C-N bond cleavage facilitated by methyl tosylate under mild conditions.
Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Directional Depolymerization of Nylon 6 to Caprolactam Monomer With Ionic Liquids as Solvent and Catalyst.ChemSusChem · 2026Article
- Microbial and Enzymatic Degradation of Nylon: Mechanisms, Diversity, and Biotechnological Application.Journal of microbiology and biotechnology · 2026Review
- Universal Approach for the Depolymerization of Polyamides via Photothermal Conversion.Journal of the American Chemical Society · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
The escalating issue of plastic "white pollution" urgently calls for efficient and sustainable recycling strategies. Herein, we propose an approach for the depolymerization of polyamides via alcoholysis, utilizing methyl tosylate as an activator to cleave robust amide C-N bonds under mild reaction conditions. This strategy facilitates the efficient conversion of diverse polyamides into high-value monomers, such as ε-caprolactam, amino acid esters, or diamines/diesters, with nearly quantitative yields and excellent selectivities. Experimental and theoretical mechanistic investigations reveal that p-toluene sulfonic acid plays a crucial role in the efficient alcoholysis of polyamides, mediating the formation of a tetrahedral intermediate through the nucleophilic attack of alcohol on the amide group. This protocol not only demonstrates exceptional applicability to complex waste plastic mixtures containing polyamides but also highlights its potential for scalable implementation, offering a practical and sustainable recycling approach for more effective management of white pollution.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.