Evidence map›Paper›PMID 41052965›Full record

ArticleRenal failure2025

Retrospective analysis of serum NELL-1 and EXT1/2: no significant predictive value for treatment response in a cohort of membranous nephropathy patients.

Yemei Dai, Rongrong Feng, Xiaowen Duan, Xiaole Su, Lihua Wang

Abstract read
In one paragraph

Article in Renal failure, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yemei DaiDepartment of Nephrology, Shanxi Medical University Second Hospital, Taiyuan, China.
Rongrong FengDepartment of Nephrology, Shanxi Medical University Second Hospital, Taiyuan, China.
Xiaowen DuanDepartment of Nephrology, Shanxi Medical University Second Hospital, Taiyuan, China.
Xiaole SuDepartment of Nephrology, Shanxi Medical University Second Hospital, Taiyuan, China.
Lihua WangDepartment of Nephrology, Shanxi Medical University Second Hospital, Taiyuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neural epidermal growth factor-like protein 1 (NELL-1) and the exostosin 1/2 complex (EXT1/2) are recently identified target antigens in membranous nephropathy (MN), yet their prevalence and clinical features in Chinese populations remain poorly characterized. This study enrolled 197 consecutive patients with biopsy-proven MN, including 186 with idiopathic membranous nephropathy (IMN) and 11 with secondary membranous nephropathy (SMN). Serum levels of NELL-1 and EXT1/2 antigens were detected

Indexed as

Glomerulonephritis, MembranousImmunosuppressive AgentsN-AcetylglucosaminyltransferasesNerve Tissue ProteinsAdultAgedAutoantibodiesBiomarkersBiopsyCalcium-Binding ProteinsChinaExostosin 1Exostosin 2FemaleHumansImmunoglobulin GAutoantibodiesBiomarkersCalcium-Binding ProteinsExostosin 1Exostosin 2Immunoglobulin GImmunosuppressive AgentsN-AcetylglucosaminyltransferasesNELL1 protein, humanNerve Tissue ProteinsReceptors, Phospholipase A2exostosin 1/2 complexIdiopathic membranous nephropathymembranous lupus nephritisneural epidermal growth factor-like 1 proteinundetermined atpical membranous nephropathy

Identifiers

PMID41052965
PMCPMC12502102

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.