Evidence map›Paper›PMID 41052793›Full record

ArticleAnimal science journal = Nihon chikusan Gakkaiho

Effects of Hitoegusa (Monostroma nitidum) Extracts on In Vitro Rumen Fermentation Profiles.

Naoya Okada, Tomomi Ban-Tokuda, Hiroki Matsui

Abstract read
In one paragraph

Article in Animal science journal = Nihon chikusan Gakkaiho. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Effects of Replacing Alfalfa withAnimals : an open access journal from MDPI · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Naoya OkadaGraduate School of Bioresources, Mie University, Tsu, Mie, Japan.
Tomomi Ban-TokudaGraduate School of Bioresources, Mie University, Tsu, Mie, Japan.ORCID https://orcid.org/0000-0001-7688-3848
Hiroki MatsuiGraduate School of Bioresources, Mie University, Tsu, Mie, Japan.ORCID https://orcid.org/0000-0002-0122-2735

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In vitro rumen fermentations were conducted using extracts of the seaweed Hitoegusa (Monostroma nitidum), which contains rhamnan sulfate, as a fermentation substrate. This study examines the metabolic utilization of Hitoegusa extract by rumen microbiota through in vitro fermentation assays. In the first incubation, the addition of Hitoegusa extract led to increased gas production and total short-chain fatty acid (SCFA) concentrations, indicative of enhanced microbial activity and substrate fermentation. Alterations in SCFA profiles suggest a potential modulation of the rumen microbial community. In the second incubation, the incubation period was extended to 96 h, and gas production was measured. In any incubation period, gas production was increased in a dose-dependent manner. Supplementation with Hitoegusa extract to wheat starch did not result in a significant reduction in methanogenesis, possibly due to the limited biodegradability of rhamnan sulfate or an insufficient release of sulfate moieties. Further investigations are required to evaluate the degradability and bioavailability of rhamnan sulfate, isolate rumen bacteria capable of degrading this polysaccharide, and characterize the relevant enzymatic and genetic mechanisms. This study highlights the potential of underutilized marine macroalgae, such as Hitoegusa, as alternative feed resources for ruminant nutrition.

Indexed as

FermentationPlant ExtractsRumenSeaweedAnimal FeedAnimalsChlorophytaEdible SeaweedsFatty Acids, VolatileGastrointestinal MicrobiomeIn Vitro TechniquesMethaneMicrobiotaTime FactorsFatty Acids, VolatileMethanePlant ExtractsHitoegusa (Monostroma nitidum) extractin vitro rumen fermentationrhamnan sulfateruminants

Identifiers

PMID41052793
PMCPMC12500386

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.