ArticleEarly intervention in psychiatry2025
Investigating Aberrant Salience in Autism Spectrum Disorder and Psychosis Risk: A Cross-Group Analysis.
Article in Early intervention in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The trial behind it
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Who cites it
4 citing papers in PubMed.
- Autistic Trait Profiles Across Mood and Psychotic Spectrum Disorders: A Transdiagnostic Outpatient Study.Journal of clinical medicine · 2026Article
- The Paradoxical Effect of Cannabis Use on Cognition in Chronic Psychotic Disorders.Pathophysiology : the official journal of the International Society for Pathophysiology · 2026Article
- Autism in Adulthood: Psychiatric Comorbidity in High-Functioning Autistic Adults in an Outpatient Clinical Population.NeuroSci · 2025Article
- Investigating Aberrant Salience in Autism Spectrum Disorder and Psychosis Risk: A Cross-Group Analysis.Early intervention in psychiatry · 2025Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
aimThis study investigates the expression of aberrant salience (AS) in individuals with autism spectrum disorder (ASD), those at clinical high risk for psychosis (CHR-P) and help-seeking individuals without formal diagnoses.
methodsNinety-nine participants, 44 males and 55 females (age range 17-39 years), met the inclusion criteria of absence of major neurological disorders, intellectual disabilities or substance-related conditions. None were receiving antipsychotic treatment. Based on clinical evaluations, participants were categorised into three groups: ASD (n = 23), Attenuated Psychosis Syndrome (APS) (n = 27) and help-seekers (n = 49). The Aberrant Salience Inventory (ASI) was administered.
resultsSignificant differences were observed in ASI total and subscale scores among groups. Post hoc analyses showed significantly higher ASI scores in the ASD and APS groups compared to help-seekers, but no significant differences between ASD and APS.
conclusionsThese findings suggest an overlap in AS processing between ASD and psychosis-spectrum conditions, supporting AS as a transdiagnostic construct.
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Registered trials
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