ArticleJapanese journal of clinical oncology2025
Practical guidance on the clinical management of ocular adverse events associated with belantamab mafodotin in patients with relapsed/refractory multiple myeloma: Recommendations from a Japanese expert panel.
Article in Japanese journal of clinical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Belantamab mafodotin, pomalidomide, and dexamethasone in Japanese patients with RRMM in the phase 3 DREAMM-8 trial.International journal of hematology · 2026Trial
- Antibody-Drug Conjugates: Pharmacotherapeutic Properties and Future Perspectives.Pharmaceutics · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
backgroundMultiple myeloma is a significant cause of mortality, and treatments for patients with relapsed/refractory multiple myeloma have limited efficacy. Treatment regimens with belantamab mafodotin have demonstrated significant improvement in progression-free survival compared with current standard-of-care regimens but have been associated with an increased risk of ocular adverse events (OAEs). These practice guidelines aim to provide recommendations to support Japanese clinicians in managing OAEs and facilitate confidence in the use of belantamab mafodotin.
methodsAn expert panel of Japanese haematologists/oncologists and ophthalmologists convened to discuss and agree on the recommendations for managing OAEs in patients treated with belantamab mafodotin.
resultsThe expert panel identified four key themes and 13 clinical questions to guide the recommendations for managing belantamab mafodotin-related OAEs in the real-world setting in Japan. The four key themes were: (i) identification of OAEs associated with belantamab mafodotin treatment; (ii) management and dose modification of belantamab mafodotin treatment for OAEs; (iii) multidisciplinary collaboration for effective management of ocular events; and (iv) a patient-centred approach to the management of OAEs.
conclusionsThe recommendations in these practice guidelines build on published clinical trial evidence and the practical experience of the expert panel to help Japanese clinicians make informed treatment decisions in the management of multiple myeloma in the real-world setting.
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