Evidence map›Paper›PMID 41052028›Full record

ArticleAmerican journal of physiology. Renal physiology2025

Inducible

Shaza Khan, Lihe Chen, Chung-Lin Chou, Syed J Khundmiri, Mark A Knepper

Abstract read
In one paragraph

Article in American journal of physiology. Renal physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shaza KhanEpithelial Systems Biology Laboratory, Systems Biology Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, United States.
Lihe ChenEpithelial Systems Biology Laboratory, Systems Biology Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, United States.ORCID 0000-0002-6207-6364
Chung-Lin ChouEpithelial Systems Biology Laboratory, Systems Biology Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, United States.ORCID 0000-0002-4878-9501
Syed J KhundmiriDepartment of Physiology and Biophysics, Howard University College of Medicine, Washington, District of Columbia, United States.ORCID 0000-0002-0364-0412
Mark A KnepperEpithelial Systems Biology Laboratory, Systems Biology Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, United States.ORCID 0000-0002-2276-8091

Funding

Solute And Water Transport In Renal EpitheliaZIAHL001285 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI KNEPPER, MARK · 2009 to 2025
$34.9M
Computational Tools for ProteomicsZIAHL006129 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI KNEPPER, MARK · 2011 to 2025
$8.1M
Computational Tools for Large-Scale Data IntegrationZIHHL006303 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI KNEPPER, MARK · 2025 to 2025
$167k
HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) ZIA-HL001285HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) ZIA-HL006129Intramural NIH HHS Z99 HL999999Intramural NIH HHS ZIA HL001285Intramural NIH HHS ZIA HL006129Intramural NIH HHS ZIH HL006303
6 · The paper itself

Abstract

Arginine vasopressin (AVP) is a peptide hormone synthesized in the hypothalamus and secreted by the posterior pituitary. Previous studies toward understanding AVP physiology relied heavily on Brattleboro rats, which have a spontaneous mutation in the

Indexed as

Arginine VasopressinKidneyTamoxifenAnimalsAquaporin 2CRISPR-Cas SystemsFemaleMaleMiceMice, Inbred C57BLMice, KnockoutAqp2 protein, mouseAquaporin 2Arginine VasopressinTamoxifenaquaporin-2collecting ductkidneytamoxifen

Identifiers

PMID41052028
PMCPMC12885232

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.