Evidence map›Paper›PMID 41051971›Full record

ArticleAnnals of medicine2025

Effect of Tai Chi combined with visual-action-sensory rehabilitation therapies on cognitive function in acute ischemic stroke: a study protocol for a randomized controlled trial.

Xuewei Guan, Meijuan Lan, Lan Ge, Qianyin Zhu, Yuanyuan Chen, Leiwen Tang, Yumei Zhong

Abstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xuewei GuanNursing Department, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China.ORCID 0009-0009-8569-5393
Meijuan LanNursing Department, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China.
Lan GeNursing Department, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China.
Qianyin ZhuNursing Department, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China.
Yuanyuan ChenNursing Department, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China.
Leiwen TangNursing Department, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China.
Yumei ZhongNursing Department, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionEarly cognitive intervention in patients with acute ischemic stroke (AIS) is associated with better outcomes. 'Visual-action-sensory' rehabilitation therapies, including action observation therapy (AOT) and sensory observation therapy (SOT) have shown great potential in restoring cognitive function. A systematic review of some studies on the therapeutic effect of Tai Chi (TC)in stroke patients suggests potential benefits on depression, anxiety, and balance function. Therefore, combining AOT with TC may enhance brain functional connectivity and provide some cognitive improvements. Here, we describe a study protocol assessing the long-term effects of TC-AOT combined with SOT on cognitive function with AIS.

methodsThis study is a dual-arm, single-center, single-blind, randomized controlled trial. A total of 86 AIS patients will be enrolled and randomly assigned in a 1:1 ratio to either the intervention group or the control group. The control group will receive conventional exercise education and follow-up. The intervention group first watched tactile stimulation followed by TC action videos, and then practiced imitating TC movements. The program will be implemented once a day for 30 min, 5 days a week for a duration of 8 weeks. Outcome measures will be assessed at baseline, week 8, and week 12. The primary outcome is global cognitive function and secondary outcomes are language, attention, executive function, memory, visuospatial ability, neuropsychological assessments, and quality of daily life.

conclusionThe study anticipates that the therapeutic program described here will help to reduce the incidence of cognitive impairment in AIS patients or delay its progression.

trial registrationWe have registered at https://www.chictr.org.cn and the registration number is: ChiCTR2400088156.

Indexed as

CognitionIschemic StrokeStroke RehabilitationTai JiAdultAgedFemaleHumansMaleMiddle AgedRandomized Controlled Trials as TopicSingle-Blind MethodTreatment Outcomeaction observation therapyAcute ischemic strokecognitive rehabilitationmirror neuronssensory observation therapy

Identifiers

PMID41051971
PMCPMC12502105

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.