ArticleAmerican journal of physiology. Lung cellular and molecular physiology2025
Dietary influence on lung injury and immune modulation in cadmium-exposed mice.
Chandrashekhar Prasad, Debolina Dasgupta, Aprajita Tripathi, Nicolas Steele, Santhosh Kumar Duraisamy, Kalyani Pyaram, Isaac Kirubakaran Sundar
Abstract read
In one paragraphArticle in American journal of physiology. Lung cellular and molecular physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from itWhat it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
7 authors.
Chandrashekhar PrasadDepartment of Internal Medicine, Division of Pulmonary Critical Care and Sleep Medicine, University of Kansas Medical Center, Kansas City, Kansas, United States.
Debolina DasguptaDepartment of Cancer Biology, University of Kansas Medical Center, Kansas City, Kansas, United States.
Aprajita TripathiDepartment of Cancer Biology, University of Kansas Medical Center, Kansas City, Kansas, United States.
Nicolas SteeleDepartment of Internal Medicine, Division of Pulmonary Critical Care and Sleep Medicine, University of Kansas Medical Center, Kansas City, Kansas, United States.ORCID 0009-0002-3466-3075 Santhosh Kumar DuraisamyDepartment of Internal Medicine, Division of Pulmonary Critical Care and Sleep Medicine, University of Kansas Medical Center, Kansas City, Kansas, United States.
Kalyani PyaramDepartment of Cancer Biology, University of Kansas Medical Center, Kansas City, Kansas, United States.ORCID 0000-0003-2744-7470 Isaac Kirubakaran SundarDepartment of Internal Medicine, Division of Pulmonary Critical Care and Sleep Medicine, University of Kansas Medical Center, Kansas City, Kansas, United States.ORCID 0000-0001-6742-3460 Funding
Mentoring CoreP20GM103418 · NIGMS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI SUSAN J. BROWN · 2012 to 2026
$63.0MPulmonary Toxicology Facility CoreP30ES005605 · NIEHS · UNIVERSITY OF IOWA · PI HANS-JOACHIM LEHMLER · 1990 to 2026
$40.5MUsing Integrated Omics to Identify Dysfunctional Genetic Mechanisms Influencing Schizophrenia and Sleep DisturbancesP20GM130423 · NIGMS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI Kalyani Pyaram, Steven Allan Soper · 2019 to 2026
$21.5MNuclear Receptor REV-ERB alpha Role in the Pathophysiology of Allergic AsthmaR01HL142543 · NHLBI · UNIVERSITY OF ROCHESTER · PI SUNDAR, ISAAC KIRUBAKARAN · 2019 to 2023
$1.9MHHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) R01HL142543KU | University of Kansas Medical Center (KUMC) Internal MedicineKU | University of Kansas Medical Center (KUMC) Lied Pre-clinical GrantKU | University of Kansas Medical Center (KUMC) University of Kansas Cancer CenterNHLBI NIH HHS R01 HL142543NIEHS NIH HHS P30 ES005605NIGMS NIH HHS P20 GM103418NIGMS NIH HHS P20 GM130423
6 · The paper itselfAbstract
Cadmium (Cd), a toxic heavy metal found in air pollution, poses serious risks to lung health due to its efficient pulmonary absorption and prolonged biological half-life. This study examines how ad libitum (AL), time-restricted feeding (TRF), and intermittent fasting (IF) influence Cd-induced lung injury and immune responses in mice. Adult male C57BL/6 mice were preacclimated to AL, TRF, or IF regimens for 3 wk, followed by intratracheal exposure to cadmium chloride (CdCl
Indexed as
CadmiumDietLung InjuryAnimalsBronchoalveolar Lavage FluidCytokinesFastingLungMaleMiceMice, Inbred C57BLSpleenCadmiumCytokinescadmiumhomeostasisintermittent fastinglung injuryT-celltime-restricted feeding
Identifiers
PMID41051968
PMCPMC12702467
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