ArticleClinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Evaluation of Hemato-Inflammatory Parameters NLR, PLR and HPR in Patients with Immune Thrombocytopenic Purpura (ITP) in South-East Iran: A Retrospective Study.
Article in Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
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Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Risk Factors and Predictive Biomarkers for Postoperative Complications in Crohn's Disease Surgery: Systematic Review.International journal of molecular sciences · 2026Pooled it
- Prognostic Significance of Inflammatory Markers in Patients with Immune Thrombocytopenia.International journal of molecular sciences · 2026Article
- Risk factors analysis and validation of early treatment non-response in children with primary ITP: a multicenter retrospective cohort study.Frontiers in immunology · 2026Article
- Emerging targeted therapies for primary immune thrombocytopenia: novel agents, combination strategies, and future directions.Frontiers in pharmacology · 2026Review
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Authors and funding
6 authors.
Funding
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Abstract
BackgroundImmune thrombocytopenic purpura (ITP) is an autoimmune hematologic disorder characterized by thrombocytopenia and clinical manifestations such as petechiae, ecchymosis, and bleeding. Recently, simple and accessible inflammatory indices including neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and hemoglobin-to-platelet ratio (HPR) have been proposed as potential biomarkers for disease assessment. The aim of this study was to evaluate the diagnostic and clinical value of NLR, PLR, and HPR in patients with ITP in Southeast Iran.MethodsThis retrospective cross-sectional study included 114 ITP patients and 115 control. Hematologic parameters and inflammatory indices (NLR, PLR, HPR) were assessed before and after treatment. Diagnostic accuracy was evaluated using receiver operating characteristic (ROC) curves.ResultsSignificant differences were observed between patients and controls across all parameters. HPR was notably higher in ITP patients. Bleeding symptoms were associated with elevated NLR and HPR (
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