Evidence map›Paper›PMID 41051691›Full record

ArticleInfection2026

Antimicrobial Stewardship in German non-university hospitals: baseline status and impact of a multifaceted AMS intervention within the prospective ID ROLL OUT study.

R Giesen, G Först, G Fink, R Allen, N Wimmesberger, D Hornuss, S Horn, F Khaleqi, S Mertins, M Schmid and 11 more

Abstract readMulticenter Study
In one paragraph

Article in Infection, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. [Requirements for the rational use of antibiotics based on antibiotic stewardship].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

R GiesenDivision of Infectious Diseases, Department of Medicine II, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany. roland.giesen@uniklinik-freiburg.de.
G FörstDivision of Infectious Diseases, Department of Medicine II, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
G FinkDivision of Infectious Diseases, Department of Medicine II, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
R AllenSection of Health Care Research and Rehabilitation Research, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
N WimmesbergerSection of Health Care Research and Rehabilitation Research, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
D HornussDivision of Infectious Diseases, Department of Medicine II, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
S HornDepartment of Medicine 2, Marienhospital Stuttgart, Stuttgart, Germany.
F KhaleqiDepartment of Medicine IV, Böblingen Hospital, Clinic Group Southwest, Böblingen, Germany.
S MertinsDepartment of Medicine II, Schwarzwald-Baar Hospital, Villingen-Schwenningen, Germany.
M SchmidDepartment of Medicine I, Hegau-Bodensee Hospital Singen, Health Association Landkreis Konstanz, Singen, Germany.
A SchmidtDepartment of Medicine, Hospital Am Eichert (Göppingen), Alb-Fils-Hospitals, Göppingen, Germany.
T TremmelDepartment of Medicine, Staufer Hospital Schwäbisch Gmünd, Ostalb Hospitals, Mutlangen, Germany.
C van UdenDepartment of Medicine I, Ostalb Hospital Aalen, Ostalb Hospitals, Aalen, Germany.
F WagnerDepartment of Medicine I, Sindelfingen Hospital, Clinic Group Southwest, Sindelfingen, Germany.
U Witten-StephanDepartment of Anesthesia and Intensive Care, Hospital Mittelbaden, Rastatt, Germany.
Y WuwerDepartment of Pneumology, Hospital St. Josef Hospital, Freiburg, Germany.
P MathéDivision of Infectious Diseases, Department of Medicine II, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
W V KernDivision of Infectious Diseases, Department of Medicine II, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
E Farin-GlattackerSection of Health Care Research and Rehabilitation Research, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
S RiegDivision of Infectious Diseases, Department of Medicine II, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
I. D. ROLL O. U. T. study group

Funding

The study was funded by the Innovation Committee of the Federal Joint Committee (G-BA) for funding proposal-ID: NVF2_2019-062
6 · The paper itself

Abstract

purposeNon-university hospitals are the major provider of inpatient care in Germany, but the extent of antimicrobial stewardship (AMS) activities in this sector is not well known. We aimed to evaluate the implementation of AMS in ten non-university hospitals in Germany.

methodsA pre-existing French score covering key AMS categories (structures, resources and actions) was adapted to the German AMS guidelines and named AMS-GER score. The score was assessed before, during and after the implementation of a bundle of AMS measures. The bundle was implemented as part of the ID ROLL OUT study - a multicentre pre-post interventional study in non-university hospitals in Germany.

resultsAt baseline, the median AMS-GER score was 37% (range 20-60%), indicating poor implementation in 9 out of 10 hospitals. The intervention resulted in a significant score improvement to 76% (range: 62-86%, p < 0.001). At the one-year follow-up after the intervention, the AMS-GER score had decreased in all hospitals (median: -13 percentage points (range: 48-80%, p = 0.015)). Hospitals with ongoing full-time AMS/ID staffing (4/10 hospitals) experienced a smaller decrease ( - 13 percentage points) than those without ( - 32 percentage points in 6/10 hospitals).

conclusionRoutine integration of AMS in a large sample of non-university hospitals in Germany is low but can be significantly improved by targeted interventions. The decline in the AMS-GER score in the follow-up phase-particularly in hospitals lacking ongoing AMS/ID staffing-highlights the need for sustained staffing and systematic benchmarking. In this context, the AMS-GER score offers a structured tool for AMS monitoring in German hospitals.

Indexed as

Anti-Bacterial AgentsAntimicrobial StewardshipHospitalsGermanyHumansProspective StudiesAnti-Bacterial AgentsAMS-GERAntibiotic stewardship (ABS)Antimicrobial stewardship (AMS)AssessmentNon-university hospitalScoreSustainability

Identifiers

PMID41051691
PMCPMC12864315

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.