Evidence map›Paper›PMID 41051686›Full record

ArticleAnnals of nuclear medicine2026

Whole-body dynamic FDG-PET/CT parametric imaging in alveolar echinococcosis.

Lars Husmann, Bert-Ram Sah, Fotis Kotasidis, Alexander Maurer, Cordula Meyer Zu Schwabedissen, Ansgar Deibel, Martin W Huellner

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Article in Annals of nuclear medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

7 authors.

Lars HusmannDepartment of Nuclear Medicine, University Hospital Zurich, University of Zurich, Raemistrasse 100, CH-8091, Zurich, Switzerland. lars.husmann@usz.ch.ORCID http://orcid.org/0000-0002-5878-0818
Bert-Ram SahDepartment of Nuclear Medicine, University Hospital Zurich, University of Zurich, Raemistrasse 100, CH-8091, Zurich, Switzerland.
Fotis KotasidisGE Healthcare, Waukesha, WI, USA.
Alexander MaurerDepartment of Nuclear Medicine, University Hospital Zurich, University of Zurich, Raemistrasse 100, CH-8091, Zurich, Switzerland.
Cordula Meyer Zu SchwabedissenDivision of Gastroenterology and Hepatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Ansgar DeibelDivision of Gastroenterology and Hepatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Martin W HuellnerDepartment of Nuclear Medicine, University Hospital Zurich, University of Zurich, Raemistrasse 100, CH-8091, Zurich, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine the role of whole-body dynamic (WBD)/Patlak parametric

methodsWe prospectively analyzed 20 PET/CT datasets performed for staging or therapy monitoring in patients with confirmed AE. Dynamic and standard static PET/CT datasets were acquired in all patients, and quantitative imaging parameters were measured in the lesion with the highest uptake (i.e., maximum standardized uptake value (SUVmax) and Patlak parameters) and compared to normal liver tissue (SUVratio and Patlak ratio).

resultsMean SUVmax in AE manifestations was 5.7 ± 3.1 (3.2-13.9), compared to 3.2 ± 0.4 (2.5-4.2) in non-infected liver tissue, respective values for Patlak were 13.0 ± 8.6 (2.7-35.5) and 4.9 ± 2.8 (0.6-12.1). SUVratio (1.8 ± 1.1; 1.0-5.2) was significantly lower (P < 0.001) than Patlak ratio (3.2 ± 3.2; 1.1-15.6). Both ratios correlated significantly with E. granulosus hydatid fluid (EgHF) antibodies (SUVratio r = 0.73, P < 0.001; Patlak ratio r = 0.85, P < 0.001).

conclusionWBD PET/CT yields higher lesion-to-background contrast and may, therefore, have the potential to increase sensitivity in the assessment of hepatic AE.

Indexed as

Echinococcosis, HepaticFluorodeoxyglucose F18Positron Emission Tomography Computed TomographyWhole Body ImagingAdultAgedEchinococcosisFemaleHumansMaleMiddle AgedYoung AdultFluorodeoxyglucose F18Alveolar echinococcosisDynamic PETFDGParametric imagingPatlak analysisPET/CT

Identifiers

PMID41051686
PMCPMC12923394

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