Evidence map›Paper›PMID 41051573›Full record

ArticleInternational urogynecology journal2026

Stress Urinary Incontinence Procedure Outcomes in the < 40-Year-Old Population: A Multicenter Study.

Ashley Huber, Hoa Nguyen, Nicole Meckes, Sujatha Narayanamoorthy, Lauren Tholemeier, Ravi Patel, Gabriella Rustia, Margot Le Neveu, Madeline Coulter, Alexander DelVlahos and 7 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in International urogynecology journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Ashley HuberDepartment of Obstetrics, Gynecology & Reproductive Sciences, Yale School of Medicine, 310 Cedar Street FMB329, New Haven, CT, 06510, USA. Ashley.huber@yale.edu.
Hoa NguyenDivision of Female Pelvic Medicine and Reconstructive Surgery, Department of Obstetrics and Gynecology, Northwestern Medicine, Chicago, IL, USA.
Nicole MeckesDepartment of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh Medical Center Magee-Womens Hospital, Pittsburgh, PA, USA.
Sujatha NarayanamoorthyDivision of Urogynecology and Reconstructive Pelvic Surgery, Department of Obstetrics and Gynecology, Mayo Clinic, Rochester, MN, USA.
Lauren TholemeierDivision of Urogynecology and Reconstructive Pelvic Surgery, Department of Obstetrics & Gynecology, University of North Carolina at Chapel Hill, and the University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, USA.
Ravi PatelDivision of Urogynecology, Department of Obstetrics and Gynecology, Mount Auburn Hospital, Harvard Medical School, Cambridge, MA, USA.
Gabriella RustiaUrology Institute, University Hospitals/ Cleveland Medical Center in Cleveland, Cleveland, OH, USA.
Margot Le NeveuUrology Institute, University Hospitals/ Cleveland Medical Center in Cleveland, Cleveland, OH, USA.
Madeline CoulterDepartment of Obstetrics and Gynecology, Vanderbilt University Medical Center, Nashville, TN, USA.
Alexander DelVlahosDepartment of Obstetrics and Gynecology and Women's Health. Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA.
Zachary SelzlerDivision of Urogynecology & Reconstructive Pelvic Surgery, Department of Obstetrics & Gynecology, Louisiana State University Health Sciences Center, New Orleans, LA, USA.
Nicholas SciosciaDepartment of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Trieu DoDepartment of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, TX, USA.
Jared FlochDivision of Pelvic Health and Urogynecology, University of Rochester Medical Center, Rochester, NY, USA.
K Marie DouglassDivision of Urogynecology and Reconstructive Pelvic Surgery, Harbor-UCLA Medical Center, Los Angeles, CA, USA.
Lisbet LundsbergDepartment of Obstetrics, Gynecology & Reproductive Sciences, Yale School of Medicine, 310 Cedar Street FMB329, New Haven, CT, 06510, USA.
Nancy RingelDepartment of Obstetrics, Gynecology & Reproductive Sciences, Yale School of Medicine, 310 Cedar Street FMB329, New Haven, CT, 06510, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesStress urinary incontinence (SUI) is a common problem affecting the quality of life of many women, but treatment outcomes in younger women are sparsely reported. We sought to evaluate SUI procedure outcomes in women < 40 years old.

methodsWe conducted a multicenter retrospective cohort study of women < 40 years old who underwent a primary SUI procedure between January 1, 2020 and July 1, 2023. We compared outcomes and complication rates of midurethral slings to periurethral bulking with polyacrylamide hydrogel (PAHG). Data was extracted by manual chart review and analyzed using descriptive statistics, comparative statistics with chi-square or Fisher exact tests, or the Wilcoxon two sample test for continuous measurements. The primary outcome was report of cure or improvement in SUI symptoms.

resultsFifteen study sites were included, with individual IRB approvals obtained at each site. A total of 377 women < 40 years old were identified who underwent a primary SUI procedure during the study period; 40 underwent periurethral bulking with PAHG and 337 underwent sling (307 (91%) retropubic, 13 (4%) transobturator, 17 (5%) single incision). Baseline demographics were similar between groups. Reported rates for cure or improved symptoms were 88.6% (n = 31/35) for PAHG and 97.8% (n = 315/324) for slings (p = 0.0156) at 4 weeks and 81.8% (n = 9/11) for PAGH and 92.9% (n = 66/71) for slings at approximately 1 year postoperative (p = 0.131). Complication rates were low in both groups.

conclusionsWomen < 40 years old who received periurethral bulking with PAHG for treatment of SUI had lower rates of cure/improvement at short-term follow-up in their SUI compared to those who received a sling.

Indexed as

Suburethral SlingsUrinary Incontinence, StressUrologic Surgical ProceduresAcrylic ResinsAdultAge FactorsFemaleHumansHydrogelsPostoperative ComplicationsRetrospective StudiesTreatment OutcomeAcrylic ResinsHydrogelspolyacrylamide gelsProcedural interventionStress urinary incontinence (SUI)

Identifiers

PMID41051573

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.