Trial reportUrolithiasis2025
Retrograde intrarenal surgery for treatment of stones in congenital anomalous kidneys: a case-matched comparative study with extracorporeal shockwave lithotripsy.
Trial report in Urolithiasis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05240170 (Retrograde Intrarenal Surgery for Treatment of Stones in Congenital Anomalous Kidneys), which is not on this map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Retrograde Intrarenal Surgery for Treatment of Stones in Congenital Anomalous Kidneys: Case Matched Comparative Study With Extracorporeal Shockwave Lithotripsy
Who cites it
0 citing papers in PubMed.
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo compare the efficacy and safety of extracorporeal shockwave lithotripsy (SWL) and retrograde intrarenal surgery (RIRS) in the management of renal stones in patients with congenital renal anomalies.
methodsIn this matched-group comparative study, we prospectively enrolled patients with congenital renal anomalies and renal stones ≤ 20 mm who underwent RIRS. These patients were matched 1:1 with those who underwent SWL at our institution. The primary outcome was the stone-free rate (SFR). Secondary outcomes included operative time, fluoroscopy time, complication rates, hospital stay, and need for retreatment.
resultsA total of 166 patients were included (83 in each group). Baseline demographic, clinical, and stone characteristics were comparable between the two groups, except that patients in the RIRS group had significantly higher BMI and stone radiodensity. The distribution of anomalies was as follows: malrotation (79.5%), horseshoe kidney (6.0%), pelvic kidney (10.8%), duplex system (2.4%), and crossed renal ectopia (1.2%). RIRS achieved a significantly higher SFR than SWL (81.9% vs. 56.6%, p < 0.001). Complication rates were comparable between the groups (RIRS: 24.1%, SWL: 20.5%), with the majority being minor (Clavien–Dindo grade I–II). RIRS was associated with a longer operative time, shorter fluoroscopy exposure, and significantly lower retreatment rates (19.3% vs. 85.5%, p < 0.001). The median hospital stay was 2 days for RIRS, while SWL was performed on an outpatient basis.
conclusionIn patients with congenital renal anomalies, RIRS provides superior stone clearance and significantly reduces the need for retreatment compared to SWL, while maintaining a comparable safety profile.
trial registrationThe trial was registered at ClinicalTrials.gov (NCT05240170) (04/02/2022).
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