Evidence map›Paper›PMID 41051374›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

Interconversions between RNS Revealed by Transient Voltammetry with Porphyrin-Modified Carbon Nanopipettes in Single Living Cells.

Hongli Cao, Dehui Yu, Yingjie Zhao, Xiaoyue Shen, Rujia Liu, Dengchao Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hongli CaoSchool of Chemical Sciences, University of Chinese Academy of Sciences, Beijing, 100049, P. R. China.
Dehui YuSchool of Chemical Sciences, University of Chinese Academy of Sciences, Beijing, 100049, P. R. China.
Yingjie ZhaoSchool of Chemical Sciences, University of Chinese Academy of Sciences, Beijing, 100049, P. R. China.
Xiaoyue ShenSchool of Chemical Sciences, University of Chinese Academy of Sciences, Beijing, 100049, P. R. China.
Rujia LiuSchool of Chemical Sciences, University of Chinese Academy of Sciences, Beijing, 100049, P. R. China.
Dengchao WangSchool of Chemical Sciences, University of Chinese Academy of Sciences, Beijing, 100049, P. R. China.ORCID https://orcid.org/0000-0002-4909-7830

Funding

National Natural Science Foundation of China 22374150
6 · The paper itself

Abstract

Reactive nitrogen species (RNS) play crucial roles in cellular signaling, but their quantification is very challenging due to low-abundant nature and complex conversions with other reactive molecules in the cells. The well-established amperometry methods have been widely used to measure the RNS inside the living cells, while the nanometer-sized tip is limited by the steady-state studies. In this paper, conductive nanopipettes (CNPs) with porphyrin complexes are functionalized, which allow direct transient voltammetry tests to differentiate and quantify the RNS based on the peak potential and current. It is shown that the oxidation of NO

Indexed as

CarbonElectrochemical TechniquesPorphyrinsReactive Nitrogen SpeciesSingle-Cell AnalysisHumansOxidation-ReductionCarbonPorphyrinsReactive Nitrogen Speciesconductive nanopipettereactive nitrogen speciessingle cell electrochemistrytransient voltammetry

Identifiers

PMID41051374
PMCPMC12752564

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.